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Mutational signature assignment heterogeneity is widespread and can be addressed by ensemble approaches

Single-base substitution (SBS) mutational signatures have become standard practice in cancer genomics. In lieu of de novo signature extraction, reference signature assignment allows users to estimate the activities of pre-established SBS signatures within individual malignancies. Several tools have...

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Detalles Bibliográficos
Autores principales:	Wu, Andy J, Perera, Akila, Kularatnarajah, Linganesan, Korsakova, Anna, Pitt, Jason J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Problem Solving Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518036/ https://www.ncbi.nlm.nih.gov/pubmed/37742051 http://dx.doi.org/10.1093/bib/bbad331

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