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FGFR families: biological functions and therapeutic interventions in tumors

There are five fibroblast growth factor receptors (FGFRs), namely, FGFR1–FGFR5. When FGFR binds to its ligand, namely, fibroblast growth factor (FGF), it dimerizes and autophosphorylates, thereby activating several key downstream pathways that play an important role in normal physiology, such as the...

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Detalles Bibliográficos
Autores principales: Liu, Qing, Huang, Jiyu, Yan, Weiwei, Liu, Zhen, Liu, Shu, Fang, Weiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518040/
https://www.ncbi.nlm.nih.gov/pubmed/37750089
http://dx.doi.org/10.1002/mco2.367

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