Cargando…
Kynureninase knockdown inhibits cisplatin resistance in vivo and in vitro and impacts the prognosis of cervical adenocarcinoma
BACKGROUND: Chemotherapy resistance is a leading cause of treatment failure in cases of cervical adenocarcinoma (ADC), and no effective treatment approach has yet been found. We previously identified the differentially expressed kynureninase (KYNU) mRNA in cervical adenocarcinoma cells (HeLa) and ce...
Autores principales: | Zhang, Jun-wen, Wang, Ya-nan, Zhong, Mei-ling, Liang, Mei-rong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518096/ https://www.ncbi.nlm.nih.gov/pubmed/37742026 http://dx.doi.org/10.1186/s13008-023-00098-3 |
Ejemplares similares
-
Mutational Activation of the NRF2 Pathway Upregulates Kynureninase Resulting in Tumor Immunosuppression and Poor Outcome in Lung Adenocarcinoma
por: Fahrmann, Johannes F., et al.
Publicado: (2022) -
Tryptophan pyrrolase, kynureninase and kynurenine transaminase activities of human renal tumours.
por: Allegri, G., et al.
Publicado: (1965) -
Kynureninase Upregulation Is a Prominent Feature of NFR2-Activated Cancers and Is Associated with Tumor Immunosuppression and Poor Prognosis
por: León-Letelier, Ricardo A., et al.
Publicado: (2023) -
Tryptophan Metabolism in Rat Liver After Administration of Tryptophan, Kynurenine Metabolites, and Kynureninase Inhibitors
por: Badawy, Abdulla A.-B., et al.
Publicado: (2016) -
Upregulated Kynurenine Pathway Enzymes in Aortic Atherosclerotic Aneurysm: Macrophage Kynureninase Downregulates Inflammation
por: Nishimura, Masanori, et al.
Publicado: (2021)