Evidence of Cardiac Involvement in a Patient With Necrotizing Autoimmune Myopathy (NAM)

Necrotizing autoimmune myopathy (NAM) is a rare inflammatory myopathy primarily affecting skeletal muscles. Cardiac involvement has been reported in immune-mediated necrotizing myopathy (IMNM), but its extent remains poorly understood. We present a unique case of a 68-year-old male with anti-signal...

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Autores principales: Khan, Omair A, Wilches, Rita M, Mehrabi, Joseph N, Tanji, Kurenai, Konka, Sarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Cardiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518158/
https://www.ncbi.nlm.nih.gov/pubmed/37750137
http://dx.doi.org/10.7759/cureus.44106
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author Khan, Omair A
Wilches, Rita M
Mehrabi, Joseph N
Tanji, Kurenai
Konka, Sarita
author_facet Khan, Omair A
Wilches, Rita M
Mehrabi, Joseph N
Tanji, Kurenai
Konka, Sarita
author_sort Khan, Omair A
collection PubMed
description Necrotizing autoimmune myopathy (NAM) is a rare inflammatory myopathy primarily affecting skeletal muscles. Cardiac involvement has been reported in immune-mediated necrotizing myopathy (IMNM), but its extent remains poorly understood. We present a unique case of a 68-year-old male with anti-signal recognition particle (SRP) antibody-positive NAM initially presenting with elevated troponin levels. Our case demonstrates cardiac involvement as the presenting feature of NAM, which is a unique feature of inflammatory myopathy.
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spelling pubmed-105181582023-09-25 Evidence of Cardiac Involvement in a Patient With Necrotizing Autoimmune Myopathy (NAM) Khan, Omair A Wilches, Rita M Mehrabi, Joseph N Tanji, Kurenai Konka, Sarita Cureus Cardiology Necrotizing autoimmune myopathy (NAM) is a rare inflammatory myopathy primarily affecting skeletal muscles. Cardiac involvement has been reported in immune-mediated necrotizing myopathy (IMNM), but its extent remains poorly understood. We present a unique case of a 68-year-old male with anti-signal recognition particle (SRP) antibody-positive NAM initially presenting with elevated troponin levels. Our case demonstrates cardiac involvement as the presenting feature of NAM, which is a unique feature of inflammatory myopathy. Cureus 2023-08-25 /pmc/articles/PMC10518158/ /pubmed/37750137 http://dx.doi.org/10.7759/cureus.44106 Text en Copyright © 2023, Khan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Khan, Omair A
Wilches, Rita M
Mehrabi, Joseph N
Tanji, Kurenai
Konka, Sarita
Evidence of Cardiac Involvement in a Patient With Necrotizing Autoimmune Myopathy (NAM)
title Evidence of Cardiac Involvement in a Patient With Necrotizing Autoimmune Myopathy (NAM)
title_full Evidence of Cardiac Involvement in a Patient With Necrotizing Autoimmune Myopathy (NAM)
title_fullStr Evidence of Cardiac Involvement in a Patient With Necrotizing Autoimmune Myopathy (NAM)
title_full_unstemmed Evidence of Cardiac Involvement in a Patient With Necrotizing Autoimmune Myopathy (NAM)
title_short Evidence of Cardiac Involvement in a Patient With Necrotizing Autoimmune Myopathy (NAM)
title_sort evidence of cardiac involvement in a patient with necrotizing autoimmune myopathy (nam)
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518158/
https://www.ncbi.nlm.nih.gov/pubmed/37750137
http://dx.doi.org/10.7759/cureus.44106
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