CD8(+) T cells maintain killing of MHC-I-negative tumor cells through the NKG2D–NKG2DL axis

The accepted paradigm for both cellular and anti-tumor immunity relies upon tumor cell killing by CD8(+) T cells recognizing cognate antigens presented in the context of target cell major histocompatibility complex (MHC) class I (MHC-I) molecules. Likewise, a classically described mechanism of tumor...

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Detalles Bibliográficos
Autores principales: Lerner, Emily C., Woroniecka, Karolina I., D’Anniballe, Vincent M., Wilkinson, Daniel S., Mohan, Aditya A., Lorrey, Selena J., Waibl-Polania, Jessica, Wachsmuth, Lucas P., Miggelbrink, Alexandra M., Jackson, Joshua D., Cui, Xiuyu, Raj, Jude A., Tomaszewski, William H., Cook, Sarah L., Sampson, John H., Patel, Anoop P., Khasraw, Mustafa, Gunn, Michael D., Fecci, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518253/
https://www.ncbi.nlm.nih.gov/pubmed/37537301
http://dx.doi.org/10.1038/s43018-023-00600-4

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