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A low dose of naloxone mitigates autoimmune hepatitis by regulating TLR4/NF-κB and Nrf2/HO-1 signaling pathways

Naloxone is a non-selective opiate receptor antagonist that is mainly used in the management of acute opioid overdose or intoxication. Previously, naloxone has been shown to have anti-inflammatory and antioxidant properties. Concanavalin A (Con A) model is a common and well established animal model...

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Detalles Bibliográficos
Autores principales: Ibrahim, Kawther Magdy, Ahmed, Hebatalla I., Ramadan, Laila, Balah, Amany
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518291/
https://www.ncbi.nlm.nih.gov/pubmed/37661242
http://dx.doi.org/10.1007/s10787-023-01327-5

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