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Effect of vinpocetine on embryonic heart rate in vitro

Vinpocetine is a readily available nutritional supplement claimed to improve memory and weight loss. However, it blocks the Ikr current essential for cardiac action potential repolarisation and Ikr inhibition can cause “torsade de pointes” arrhythmias and sudden death. Moreover, Ikr blockers have ex...

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Detalles Bibliográficos
Autores principales: Ritchie, Helen Elizabeth, Polson, Jaimie W., Xia, Andrea, Webster, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518341/
https://www.ncbi.nlm.nih.gov/pubmed/37753450
http://dx.doi.org/10.1016/j.crtox.2023.100125