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Generation of embryo-like structures from mouse embryonic stem cells treated with a chemical inhibitor of SUMOylation and cultured in microdroplets

The field of stem cell-based embryo-like models is rapidly evolving, providing in vitro models of in utero stages of mammalian development. Here, we detail steps to first establish adherent spheroids composed of three cell types from mouse embryonic stem cells solely treated with a chemical inhibito...

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Detalles Bibliográficos
Autores principales: Traboulsi, Tatiana, Sart, Sébastien, Baroud, Charles N., Dejean, Anne, Cossec, Jack-Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518363/
https://www.ncbi.nlm.nih.gov/pubmed/37721864
http://dx.doi.org/10.1016/j.xpro.2023.102573