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Varying presentations of immune checkpoint inhibitor-associated myocarditis: A case report of the clinical characteristics and outcomes of three patients

• ICI-associated myocarditis is a rare clinical entity, but one with an exceedingly high mortality rate. • The condition can present with a wide variety of manifestations. Thus, clinical suspicion for the diagnosis should remain elevated in at-risk patients receiving immunotherapy. • Early diagnosis...

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Detalles Bibliográficos
Autores principales: Fox, Brandon, Backes, Floor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518436/
https://www.ncbi.nlm.nih.gov/pubmed/37752990
http://dx.doi.org/10.1016/j.gore.2023.101271
Descripción
Sumario:• ICI-associated myocarditis is a rare clinical entity, but one with an exceedingly high mortality rate. • The condition can present with a wide variety of manifestations. Thus, clinical suspicion for the diagnosis should remain elevated in at-risk patients receiving immunotherapy. • Early diagnosis and prompt initiation of high-dose steroids are key to optimizing patient outcomes.