Varying presentations of immune checkpoint inhibitor-associated myocarditis: A case report of the clinical characteristics and outcomes of three patients

• ICI-associated myocarditis is a rare clinical entity, but one with an exceedingly high mortality rate. • The condition can present with a wide variety of manifestations. Thus, clinical suspicion for the diagnosis should remain elevated in at-risk patients receiving immunotherapy. • Early diagnosis...

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Detalles Bibliográficos
Autores principales: Fox, Brandon, Backes, Floor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518436/
https://www.ncbi.nlm.nih.gov/pubmed/37752990
http://dx.doi.org/10.1016/j.gore.2023.101271
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author Fox, Brandon
Backes, Floor
author_facet Fox, Brandon
Backes, Floor
author_sort Fox, Brandon
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description • ICI-associated myocarditis is a rare clinical entity, but one with an exceedingly high mortality rate. • The condition can present with a wide variety of manifestations. Thus, clinical suspicion for the diagnosis should remain elevated in at-risk patients receiving immunotherapy. • Early diagnosis and prompt initiation of high-dose steroids are key to optimizing patient outcomes.
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spelling pubmed-105184362023-09-26 Varying presentations of immune checkpoint inhibitor-associated myocarditis: A case report of the clinical characteristics and outcomes of three patients Fox, Brandon Backes, Floor Gynecol Oncol Rep Case Report • ICI-associated myocarditis is a rare clinical entity, but one with an exceedingly high mortality rate. • The condition can present with a wide variety of manifestations. Thus, clinical suspicion for the diagnosis should remain elevated in at-risk patients receiving immunotherapy. • Early diagnosis and prompt initiation of high-dose steroids are key to optimizing patient outcomes. Elsevier 2023-09-14 /pmc/articles/PMC10518436/ /pubmed/37752990 http://dx.doi.org/10.1016/j.gore.2023.101271 Text en © 2023 Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Fox, Brandon
Backes, Floor
Varying presentations of immune checkpoint inhibitor-associated myocarditis: A case report of the clinical characteristics and outcomes of three patients
title Varying presentations of immune checkpoint inhibitor-associated myocarditis: A case report of the clinical characteristics and outcomes of three patients
title_full Varying presentations of immune checkpoint inhibitor-associated myocarditis: A case report of the clinical characteristics and outcomes of three patients
title_fullStr Varying presentations of immune checkpoint inhibitor-associated myocarditis: A case report of the clinical characteristics and outcomes of three patients
title_full_unstemmed Varying presentations of immune checkpoint inhibitor-associated myocarditis: A case report of the clinical characteristics and outcomes of three patients
title_short Varying presentations of immune checkpoint inhibitor-associated myocarditis: A case report of the clinical characteristics and outcomes of three patients
title_sort varying presentations of immune checkpoint inhibitor-associated myocarditis: a case report of the clinical characteristics and outcomes of three patients
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518436/
https://www.ncbi.nlm.nih.gov/pubmed/37752990
http://dx.doi.org/10.1016/j.gore.2023.101271
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AT backesfloor varyingpresentationsofimmunecheckpointinhibitorassociatedmyocarditisacasereportoftheclinicalcharacteristicsandoutcomesofthreepatients

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