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EGFR trafficking: effect of dimerization, dynamics, and mutation

Spontaneous dimerization of EGF receptors (EGFR) and dysregulation of EGFR signaling has been associated with the development of different cancers. Under normal physiological conditions and to maintain homeostatic cell growth, once EGFR signaling occurs, it needs to be attenuated. Activated EGFRs ar...

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Detalles Bibliográficos
Autores principales:	Schultz, Destiny F., Billadeau, Daniel D., Jois, Seetharama D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518470/ https://www.ncbi.nlm.nih.gov/pubmed/37752992 http://dx.doi.org/10.3389/fonc.2023.1258371

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