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IGF2BP3 mediates the mRNA degradation of NF1 to promote triple‐negative breast cancer progression via an m6A‐dependent manner
BACKGROUND: N6‐methyladenosine (m6A) is an abundant reversible modification in eukaryotic mRNAs. Emerging evidences indicate that m6A modification plays a vital role in tumourigenesis. As a crucial reader of m6A, IGF2BP3 usually mediates the stabilisation of mRNAs via an m6A‐dependent manner. But th...
Autores principales: | Zhang, Xu, Shi, Liang, Sun, Han‐Dong, Wang, Zi‐Wen, Xu, Feng, Wei, Ji‐Fu, Ding, Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518495/ https://www.ncbi.nlm.nih.gov/pubmed/37743642 http://dx.doi.org/10.1002/ctm2.1427 |
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