Multisystem Inflammatory Syndrome in an Adult on Hemodialysis with Markedly Elevated Procalcitonin and Ferritin Levels

A 21-year-old man on hemodialysis was hospitalized for coronavirus disease 2019 (COVID-19) pneumonia. After admission, he had a persistent high fever and developed erythema induratum on his extremities. Laboratory tests conducted 25 days after onset showed markedly increased procalcitonin (PCT) leve...

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Autores principales: Asano, Shuichi, Shibata, Tomofumi, Tsunoda, Yohei, Ishii, Azusa, Kayukawa, Takafumi, Kobayashi, Masahiro, Orinaka, Masami, Miyamatsu, Shoko, Ryuge, Yoshio, Kato, Kimihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518544/
https://www.ncbi.nlm.nih.gov/pubmed/37344434
http://dx.doi.org/10.2169/internalmedicine.1832-23
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author Asano, Shuichi
Shibata, Tomofumi
Tsunoda, Yohei
Ishii, Azusa
Kayukawa, Takafumi
Kobayashi, Masahiro
Orinaka, Masami
Miyamatsu, Shoko
Ryuge, Yoshio
Kato, Kimihiro
author_facet Asano, Shuichi
Shibata, Tomofumi
Tsunoda, Yohei
Ishii, Azusa
Kayukawa, Takafumi
Kobayashi, Masahiro
Orinaka, Masami
Miyamatsu, Shoko
Ryuge, Yoshio
Kato, Kimihiro
author_sort Asano, Shuichi
collection PubMed
description A 21-year-old man on hemodialysis was hospitalized for coronavirus disease 2019 (COVID-19) pneumonia. After admission, he had a persistent high fever and developed erythema induratum on his extremities. Laboratory tests conducted 25 days after onset showed markedly increased procalcitonin (PCT) levels (>100 ng/mL). The patient developed impaired consciousness and hypotensive shock and required endotracheal intubation. Based on the presence of erythema induratum and multiorgan dysfunction, he was diagnosed with multisystem inflammatory syndrome (MIS). The MIS resolved after treatment with intravenous immunoglobulin and methylprednisolone. This report illustrates that MIS can occur in adults and may be accompanied by high PCT levels.
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spelling pubmed-105185442023-09-26 Multisystem Inflammatory Syndrome in an Adult on Hemodialysis with Markedly Elevated Procalcitonin and Ferritin Levels Asano, Shuichi Shibata, Tomofumi Tsunoda, Yohei Ishii, Azusa Kayukawa, Takafumi Kobayashi, Masahiro Orinaka, Masami Miyamatsu, Shoko Ryuge, Yoshio Kato, Kimihiro Intern Med Case Report A 21-year-old man on hemodialysis was hospitalized for coronavirus disease 2019 (COVID-19) pneumonia. After admission, he had a persistent high fever and developed erythema induratum on his extremities. Laboratory tests conducted 25 days after onset showed markedly increased procalcitonin (PCT) levels (>100 ng/mL). The patient developed impaired consciousness and hypotensive shock and required endotracheal intubation. Based on the presence of erythema induratum and multiorgan dysfunction, he was diagnosed with multisystem inflammatory syndrome (MIS). The MIS resolved after treatment with intravenous immunoglobulin and methylprednisolone. This report illustrates that MIS can occur in adults and may be accompanied by high PCT levels. The Japanese Society of Internal Medicine 2023-06-21 2023-09-01 /pmc/articles/PMC10518544/ /pubmed/37344434 http://dx.doi.org/10.2169/internalmedicine.1832-23 Text en Copyright © 2023 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Asano, Shuichi
Shibata, Tomofumi
Tsunoda, Yohei
Ishii, Azusa
Kayukawa, Takafumi
Kobayashi, Masahiro
Orinaka, Masami
Miyamatsu, Shoko
Ryuge, Yoshio
Kato, Kimihiro
Multisystem Inflammatory Syndrome in an Adult on Hemodialysis with Markedly Elevated Procalcitonin and Ferritin Levels
title Multisystem Inflammatory Syndrome in an Adult on Hemodialysis with Markedly Elevated Procalcitonin and Ferritin Levels
title_full Multisystem Inflammatory Syndrome in an Adult on Hemodialysis with Markedly Elevated Procalcitonin and Ferritin Levels
title_fullStr Multisystem Inflammatory Syndrome in an Adult on Hemodialysis with Markedly Elevated Procalcitonin and Ferritin Levels
title_full_unstemmed Multisystem Inflammatory Syndrome in an Adult on Hemodialysis with Markedly Elevated Procalcitonin and Ferritin Levels
title_short Multisystem Inflammatory Syndrome in an Adult on Hemodialysis with Markedly Elevated Procalcitonin and Ferritin Levels
title_sort multisystem inflammatory syndrome in an adult on hemodialysis with markedly elevated procalcitonin and ferritin levels
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518544/
https://www.ncbi.nlm.nih.gov/pubmed/37344434
http://dx.doi.org/10.2169/internalmedicine.1832-23
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