Life-threatening Vasospastic Angina Induced by Carteolol Eye Drops

Vasospastic angina (VSA) can be worsened by oral nonselective beta-blockers. Ophthalmic carteolol eye drops are nonselective beta-blockers and effective against glaucoma and ocular hypertension. Systemic effects of ophthalmic beta-blockers on VSA have not yet been reported. We herein report a case o...

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Detalles Bibliográficos
Autores principales: Eto, Ryo, Kawano, Hiroaki, Suzuki, Ayaka, Akashi, Ryohei, Ikeda, Satoshi, Maemura, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518556/
https://www.ncbi.nlm.nih.gov/pubmed/36476545
http://dx.doi.org/10.2169/internalmedicine.0495-22
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author Eto, Ryo
Kawano, Hiroaki
Suzuki, Ayaka
Akashi, Ryohei
Ikeda, Satoshi
Maemura, Koji
author_facet Eto, Ryo
Kawano, Hiroaki
Suzuki, Ayaka
Akashi, Ryohei
Ikeda, Satoshi
Maemura, Koji
author_sort Eto, Ryo
collection PubMed
description Vasospastic angina (VSA) can be worsened by oral nonselective beta-blockers. Ophthalmic carteolol eye drops are nonselective beta-blockers and effective against glaucoma and ocular hypertension. Systemic effects of ophthalmic beta-blockers on VSA have not yet been reported. We herein report a case of VSA that developed after a patient started carteolol eye drops for ocular hypertension. Even though benidipine, a calcium channel blocker, was started, a VSA attack with incessant non-sustained ventricular tachycardia occurred. Once the carteolol eyedrops were discontinued, the VSA resolved. This case demonstrates that carteolol eye drops can induce life-threatening VSA.
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spelling pubmed-105185562023-09-26 Life-threatening Vasospastic Angina Induced by Carteolol Eye Drops Eto, Ryo Kawano, Hiroaki Suzuki, Ayaka Akashi, Ryohei Ikeda, Satoshi Maemura, Koji Intern Med Case Report Vasospastic angina (VSA) can be worsened by oral nonselective beta-blockers. Ophthalmic carteolol eye drops are nonselective beta-blockers and effective against glaucoma and ocular hypertension. Systemic effects of ophthalmic beta-blockers on VSA have not yet been reported. We herein report a case of VSA that developed after a patient started carteolol eye drops for ocular hypertension. Even though benidipine, a calcium channel blocker, was started, a VSA attack with incessant non-sustained ventricular tachycardia occurred. Once the carteolol eyedrops were discontinued, the VSA resolved. This case demonstrates that carteolol eye drops can induce life-threatening VSA. The Japanese Society of Internal Medicine 2022-12-07 2023-09-01 /pmc/articles/PMC10518556/ /pubmed/36476545 http://dx.doi.org/10.2169/internalmedicine.0495-22 Text en Copyright © 2023 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Eto, Ryo
Kawano, Hiroaki
Suzuki, Ayaka
Akashi, Ryohei
Ikeda, Satoshi
Maemura, Koji
Life-threatening Vasospastic Angina Induced by Carteolol Eye Drops
title Life-threatening Vasospastic Angina Induced by Carteolol Eye Drops
title_full Life-threatening Vasospastic Angina Induced by Carteolol Eye Drops
title_fullStr Life-threatening Vasospastic Angina Induced by Carteolol Eye Drops
title_full_unstemmed Life-threatening Vasospastic Angina Induced by Carteolol Eye Drops
title_short Life-threatening Vasospastic Angina Induced by Carteolol Eye Drops
title_sort life-threatening vasospastic angina induced by carteolol eye drops
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518556/
https://www.ncbi.nlm.nih.gov/pubmed/36476545
http://dx.doi.org/10.2169/internalmedicine.0495-22
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