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Plasma proteins and onset of type 2 diabetes and diabetic complications: Proteome-wide Mendelian randomization and colocalization analyses

We conduct proteome-wide Mendelian randomization and colocalization analyses to decipher the associations of blood proteins with the risk of type 2 diabetes and diabetic complications. Genetic data on plasma proteome are obtained from 54,306 UK Biobank participants and 35,559 Icelanders. Summary-lev...

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Detalles Bibliográficos
Autores principales: Yuan, Shuai, Xu, Fengzhe, Li, Xue, Chen, Jie, Zheng, Jie, Mantzoros, Christos S., Larsson, Susanna C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518626/
https://www.ncbi.nlm.nih.gov/pubmed/37652020
http://dx.doi.org/10.1016/j.xcrm.2023.101174