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Cucurbitacin B induces apoptosis in colorectal cells through reactive oxygen species generation and endoplasmic reticulum stress pathways

Cucurbitacin B (CuB) is a member of the cucurbitacin family, which has shown potent anticancer pharmacological activity. Prolonged or severe endoplasmic reticulum stress (ERS) induces apoptosis; therefore, the present study investigated whether CuB may activate the ERS pathway to induce apoptosis. H...

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Detalles Bibliográficos
Autores principales:	Huang, Jian-Lan, Liang, Li, Xie, Pei-En, Sun, Wei-Liang, Wang, Li, Cai, Zheng-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518646/ https://www.ncbi.nlm.nih.gov/pubmed/37753296 http://dx.doi.org/10.3892/etm.2023.12183

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