High-Throughput Screening and Proteomic Characterization of Compounds Targeting Myeloid-Derived Suppressor Cells

Myeloid-derived suppressor cells (MDSC) are a heterogeneous cell population of incompletely differentiated immune cells. They are known to suppress T cell activity and are implicated in multiple chronic diseases, which make them an attractive cell population for drug discovery. Here, we characterize...

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Detalles Bibliográficos
Autores principales: Krumm, Johannes, Petrova, Elissaveta, Lechner, Severin, Mergner, Julia, Boehm, Hans-Henning, Prestipino, Alessandro, Steinbrunn, Dominik, Deline, Marshall L., Koetzner, Lisa, Schindler, Christina, Helming, Laura, Fromme, Tobias, Klingenspor, Martin, Hahne, Hannes, Pieck, Jan-Carsten, Kuster, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518717/
https://www.ncbi.nlm.nih.gov/pubmed/37586548
http://dx.doi.org/10.1016/j.mcpro.2023.100632

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