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High-fat diet reveals the impact of Sar1b defects on lipid and lipoprotein profile and cholesterol metabolism

Biallelic pathogenic variants of the Sar1b gene cause chylomicron retention disease (CRD) whose central phenotype is the inability to secrete chylomicrons. Patients with CRD experience numerous clinical symptoms such as gastrointestinal, hepatic, neuromuscular, ophthalmic, and cardiological abnormal...

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Detalles Bibliográficos
Autores principales:	Auclair, Nickolas, Sané, Alain T., Ahmarani, Léna, Ould-Chikh, Nour-El-Houda, Patey, Nathalie, Beaulieu, Jean-François, Delvin, Edgard, Spahis, Schohraya, Levy, Emile
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518719/ https://www.ncbi.nlm.nih.gov/pubmed/37558128 http://dx.doi.org/10.1016/j.jlr.2023.100423

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