Machine-learning based integrating bulk and single-cell RNA sequencing reveals the SLC38A5-CCL5 signaling as a promising target for clear cell renal cell carcinoma treatment

Cancer-associated fibroblasts paly critical roles in regulating cancer cell biological properties by intricate and dynamic communication networks. But the mechanism of CAFs in clear cell renal cell carcinoma (ccRCC) is not clear. In our study, we identified CAFs and malignant cells from the integrat...

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Detalles Bibliográficos
Autores principales: Chen, Hualin, Yang, Wenjie, Ma, Lin, Li, Yingjie, Ji, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518726/
https://www.ncbi.nlm.nih.gov/pubmed/37722291
http://dx.doi.org/10.1016/j.tranon.2023.101790

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