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Data sets of human and mouse protein kinase inhibitors with curated activity data including covalent inhibitors

AIM: Generation of high-quality data sets of protein kinase inhibitors (PKIs). METHODOLOGY: Publicly available PKIs with reliable activity data were curated. PKIs with very weak activity were classified as inactive. Analogue series and PKIs containing reactive groups (warheads) enabling covalent inh...

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Detalles Bibliográficos
Autores principales: Xerxa, Elena, Bajorath, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518807/
https://www.ncbi.nlm.nih.gov/pubmed/37752915
http://dx.doi.org/10.2144/fsoa-2023-0088