A primary hepatic lymphoma in a patient with Crohn's disease receiving thiopurine and anti-TNF therapy: a case report

Primary hepatic lymphoma is a rare variant of non-Hodgkin's lymphoma with an incidence of 0.016% of all non-Hodgkin lymphomas. The most common histologic subtype is large diffuse B-cell lymphoma. Pathogenesis is not clearly established and undergoing immunosuppressive therapy has been proposed...

Descripción completa

Detalles Bibliográficos
Autores principales: Merhaben, Salma, Ayadi, Shema, Tangour, Monia, Boujelbene, Nadia, Ghariani, Rayfa, Mouelhi, Leila, Merhaben, Fathi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518835/
https://www.ncbi.nlm.nih.gov/pubmed/37753362
http://dx.doi.org/10.2144/fsoa-2023-0082
_version_ 1785109603095150592
author Merhaben, Salma
Ayadi, Shema
Tangour, Monia
Boujelbene, Nadia
Ghariani, Rayfa
Mouelhi, Leila
Merhaben, Fathi
author_facet Merhaben, Salma
Ayadi, Shema
Tangour, Monia
Boujelbene, Nadia
Ghariani, Rayfa
Mouelhi, Leila
Merhaben, Fathi
author_sort Merhaben, Salma
collection PubMed
description Primary hepatic lymphoma is a rare variant of non-Hodgkin's lymphoma with an incidence of 0.016% of all non-Hodgkin lymphomas. The most common histologic subtype is large diffuse B-cell lymphoma. Pathogenesis is not clearly established and undergoing immunosuppressive therapy has been proposed as a risk factor for primary hepatic lymphoma. We report an intriguing case study, featuring a 23-year-old male patient with Crohn's Disease who had been receiving a combination therapy of thiopurine and anti-TNF for 6 years and was diagnosed with primary hepatic diffuse large B-cell lymphoma.
format Online
Article
Text
id pubmed-10518835
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Future Science Ltd
record_format MEDLINE/PubMed
spelling pubmed-105188352023-09-26 A primary hepatic lymphoma in a patient with Crohn's disease receiving thiopurine and anti-TNF therapy: a case report Merhaben, Salma Ayadi, Shema Tangour, Monia Boujelbene, Nadia Ghariani, Rayfa Mouelhi, Leila Merhaben, Fathi Future Sci OA Case Report Primary hepatic lymphoma is a rare variant of non-Hodgkin's lymphoma with an incidence of 0.016% of all non-Hodgkin lymphomas. The most common histologic subtype is large diffuse B-cell lymphoma. Pathogenesis is not clearly established and undergoing immunosuppressive therapy has been proposed as a risk factor for primary hepatic lymphoma. We report an intriguing case study, featuring a 23-year-old male patient with Crohn's Disease who had been receiving a combination therapy of thiopurine and anti-TNF for 6 years and was diagnosed with primary hepatic diffuse large B-cell lymphoma. Future Science Ltd 2023-08-28 /pmc/articles/PMC10518835/ /pubmed/37753362 http://dx.doi.org/10.2144/fsoa-2023-0082 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Case Report
Merhaben, Salma
Ayadi, Shema
Tangour, Monia
Boujelbene, Nadia
Ghariani, Rayfa
Mouelhi, Leila
Merhaben, Fathi
A primary hepatic lymphoma in a patient with Crohn's disease receiving thiopurine and anti-TNF therapy: a case report
title A primary hepatic lymphoma in a patient with Crohn's disease receiving thiopurine and anti-TNF therapy: a case report
title_full A primary hepatic lymphoma in a patient with Crohn's disease receiving thiopurine and anti-TNF therapy: a case report
title_fullStr A primary hepatic lymphoma in a patient with Crohn's disease receiving thiopurine and anti-TNF therapy: a case report
title_full_unstemmed A primary hepatic lymphoma in a patient with Crohn's disease receiving thiopurine and anti-TNF therapy: a case report
title_short A primary hepatic lymphoma in a patient with Crohn's disease receiving thiopurine and anti-TNF therapy: a case report
title_sort primary hepatic lymphoma in a patient with crohn's disease receiving thiopurine and anti-tnf therapy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518835/
https://www.ncbi.nlm.nih.gov/pubmed/37753362
http://dx.doi.org/10.2144/fsoa-2023-0082
work_keys_str_mv AT merhabensalma aprimaryhepaticlymphomainapatientwithcrohnsdiseasereceivingthiopurineandantitnftherapyacasereport
AT ayadishema aprimaryhepaticlymphomainapatientwithcrohnsdiseasereceivingthiopurineandantitnftherapyacasereport
AT tangourmonia aprimaryhepaticlymphomainapatientwithcrohnsdiseasereceivingthiopurineandantitnftherapyacasereport
AT boujelbenenadia aprimaryhepaticlymphomainapatientwithcrohnsdiseasereceivingthiopurineandantitnftherapyacasereport
AT gharianirayfa aprimaryhepaticlymphomainapatientwithcrohnsdiseasereceivingthiopurineandantitnftherapyacasereport
AT mouelhileila aprimaryhepaticlymphomainapatientwithcrohnsdiseasereceivingthiopurineandantitnftherapyacasereport
AT merhabenfathi aprimaryhepaticlymphomainapatientwithcrohnsdiseasereceivingthiopurineandantitnftherapyacasereport
AT merhabensalma primaryhepaticlymphomainapatientwithcrohnsdiseasereceivingthiopurineandantitnftherapyacasereport
AT ayadishema primaryhepaticlymphomainapatientwithcrohnsdiseasereceivingthiopurineandantitnftherapyacasereport
AT tangourmonia primaryhepaticlymphomainapatientwithcrohnsdiseasereceivingthiopurineandantitnftherapyacasereport
AT boujelbenenadia primaryhepaticlymphomainapatientwithcrohnsdiseasereceivingthiopurineandantitnftherapyacasereport
AT gharianirayfa primaryhepaticlymphomainapatientwithcrohnsdiseasereceivingthiopurineandantitnftherapyacasereport
AT mouelhileila primaryhepaticlymphomainapatientwithcrohnsdiseasereceivingthiopurineandantitnftherapyacasereport
AT merhabenfathi primaryhepaticlymphomainapatientwithcrohnsdiseasereceivingthiopurineandantitnftherapyacasereport

Ejemplares similares