A Case of Inflammatory Pseudotumour Masquerading as Hepatocellular Carcinoma

Inflammatory pseudotumors (IPTs) of the liver can mimic malignant lesions. As the name implies, they are usually associated with an inflammatory process and usually regress with the treatment of the underlying pathology. We report a case of a 67-year-old female who presented with right upper quadran...

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Autores principales: Rajamanickam Chandrasekaran, Kalki, Aftab, Syed, Al Jajeh, Issam, Kumar, Rajneesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518897/
https://www.ncbi.nlm.nih.gov/pubmed/37753063
http://dx.doi.org/10.7759/cureus.45897
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author Rajamanickam Chandrasekaran, Kalki
Aftab, Syed
Al Jajeh, Issam
Kumar, Rajneesh
author_facet Rajamanickam Chandrasekaran, Kalki
Aftab, Syed
Al Jajeh, Issam
Kumar, Rajneesh
author_sort Rajamanickam Chandrasekaran, Kalki
collection PubMed
description Inflammatory pseudotumors (IPTs) of the liver can mimic malignant lesions. As the name implies, they are usually associated with an inflammatory process and usually regress with the treatment of the underlying pathology. We report a case of a 67-year-old female who presented with right upper quadrant pain, deranged liver enzymes, elevated tumor markers [alpha-fetoprotein (AFP) and CA 19-9], and a large liver mass on imaging, suspected to be hepatocellular carcinoma (HCC). She was eventually diagnosed with IPT complicating the liver inflammation due to autoimmune hepatitis (AIH). She responded well to treatment with steroids and immunosuppressive therapy.
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spelling pubmed-105188972023-09-26 A Case of Inflammatory Pseudotumour Masquerading as Hepatocellular Carcinoma Rajamanickam Chandrasekaran, Kalki Aftab, Syed Al Jajeh, Issam Kumar, Rajneesh Cureus Pathology Inflammatory pseudotumors (IPTs) of the liver can mimic malignant lesions. As the name implies, they are usually associated with an inflammatory process and usually regress with the treatment of the underlying pathology. We report a case of a 67-year-old female who presented with right upper quadrant pain, deranged liver enzymes, elevated tumor markers [alpha-fetoprotein (AFP) and CA 19-9], and a large liver mass on imaging, suspected to be hepatocellular carcinoma (HCC). She was eventually diagnosed with IPT complicating the liver inflammation due to autoimmune hepatitis (AIH). She responded well to treatment with steroids and immunosuppressive therapy. Cureus 2023-09-25 /pmc/articles/PMC10518897/ /pubmed/37753063 http://dx.doi.org/10.7759/cureus.45897 Text en Copyright © 2023, Rajamanickam Chandrasekaran et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Rajamanickam Chandrasekaran, Kalki
Aftab, Syed
Al Jajeh, Issam
Kumar, Rajneesh
A Case of Inflammatory Pseudotumour Masquerading as Hepatocellular Carcinoma
title A Case of Inflammatory Pseudotumour Masquerading as Hepatocellular Carcinoma
title_full A Case of Inflammatory Pseudotumour Masquerading as Hepatocellular Carcinoma
title_fullStr A Case of Inflammatory Pseudotumour Masquerading as Hepatocellular Carcinoma
title_full_unstemmed A Case of Inflammatory Pseudotumour Masquerading as Hepatocellular Carcinoma
title_short A Case of Inflammatory Pseudotumour Masquerading as Hepatocellular Carcinoma
title_sort case of inflammatory pseudotumour masquerading as hepatocellular carcinoma
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518897/
https://www.ncbi.nlm.nih.gov/pubmed/37753063
http://dx.doi.org/10.7759/cureus.45897
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