Cargando…

Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization

BACKGROUND: Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors. New drug targets and proteins that would assist sensitive PPGL imagining could improve therapy and quality of life of patients with PPGL, namely those with recurrent or metastatic disease. Using a combined prote...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vit, Ondrej, Talacko, Pavel, Musil, Zdenek, Hartmann, Igor, Pacak, Karel, Petrak, Jiri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518975/ https://www.ncbi.nlm.nih.gov/pubmed/37749499 http://dx.doi.org/10.1186/s12014-023-09428-7

Ejemplares similares

Deep Membrane Proteome Profiling Reveals Overexpression of Prostate-Specific Membrane Antigen (PSMA) in High-Risk Human Paraganglioma and Pheochromocytoma, Suggesting New Theranostic Opportunity
por: Vit, Ondrej, et al.
Publicado: (2021)

Pheochromocytoma (PHEO) and Paraganglioma (PGL)
por: Pacak, Karel, et al.
Publicado: (2019)

New insights on the pathogenesis of paraganglioma and pheochromocytoma
por: Kantorovich, Vitaly, et al.
Publicado: (2018)

PD-L1 expression and association with genetic background in pheochromocytoma and paraganglioma
por: Hadrava Vanova, Katerina, et al.
Publicado: (2022)

Emerging Treatments for Advanced/Metastatic Pheochromocytoma and Paraganglioma
por: Ilanchezhian, Maran, et al.
Publicado: (2020)

Personalized Management of Pheochromocytoma and Paraganglioma
por: Nölting, Svenja, et al.
Publicado: (2021)

Novel Germline SUCLG2 Mutations in Patients With Pheochromocytoma and Paraganglioma
por: Vanova, Katerina Hadrava, et al.
Publicado: (2021)

Pheochromocytoma and Paraganglioma: Current Functional and Future Molecular Imaging
por: Blanchet, Elise M., et al.
Publicado: (2012)

Pheochromocytomas and Paragangliomas: From Genetic Diversity to Targeted Therapies
por: Pang, Ying, et al.
Publicado: (2019)

Postoperative Management in Patients with Pheochromocytoma and Paraganglioma
por: Mamilla, Divya, et al.
Publicado: (2019)

Reactive Oxygen Species: A Promising Therapeutic Target for SDHx-Mutated Pheochromocytoma and Paraganglioma
por: Hadrava Vanova, Katerina, et al.
Publicado: (2021)

FGF21 Levels in Pheochromocytoma/Functional Paraganglioma
por: Klímová, Judita, et al.
Publicado: (2019)

Hypermetabolism and Substrate Utilization Rates in Pheochromocytoma and Functional Paraganglioma
por: Petrák, Ondřej, et al.
Publicado: (2022)

Clinically Advanced Pheochromocytomas and Paragangliomas: A Comprehensive Genomic Profiling Study
por: Bratslavsky, Gennady, et al.
Publicado: (2021)

Risk of complications after core needle biopsy in pheochromocytoma/paraganglioma
por: Zhang, Liang, et al.
Publicado: (2023)

Gene Profile of Adipose Tissue of Patients with Pheochromocytoma/Paraganglioma
por: Klímová, Judita, et al.
Publicado: (2022)

High-Throughput Screening for the Identification of New Therapeutic Options for Metastatic Pheochromocytoma and Paraganglioma
por: Giubellino, Alessio, et al.
Publicado: (2014)

Pediatric Metastatic Pheochromocytoma and Paraganglioma: Clinical Presentation and Diagnosis, Genetics, and Therapeutic Approaches
por: Kuo, Mickey J. M., et al.
Publicado: (2022)

Management of pheochromocytomas and paragangliomas: Review of current diagnosis and treatment options
por: Eid, Michal, et al.
Publicado: (2023)

New Insights on the Genetics of Pheochromocytoma and Paraganglioma and Its Clinical Implications
por: Jhawar, Sakshi, et al.
Publicado: (2022)

External Beam Radiation Therapy in Treatment of Malignant Pheochromocytoma and Paraganglioma
por: Vogel, Jennifer, et al.
Publicado: (2014)

Somatostatin Receptors and Analogs in Pheochromocytoma and Paraganglioma: Old Players in a New Precision Medicine World
por: Patel, Mayank, et al.
Publicado: (2021)

PSUN27 Largest Cohort of Cervical Spine Metastases of Pheochromocytoma/Paraganglioma in the Setting of SDHB Mutation
por: Pacak, Karel, et al.
Publicado: (2022)

SAT305 Clinical Characteristics And Outcomes Of Patient With Metastatic Pheochromocytoma/Paraganglioma (PPGL) And Extreme Elevated Biochemistry
por: Prodanov, Tamara, et al.
Publicado: (2023)

Current Management of Pheochromocytoma/Paraganglioma: A Guide for the Practicing Clinician in the Era of Precision Medicine
por: Nölting, Svenja, et al.
Publicado: (2019)

Targeting NRF2-Governed Glutathione Synthesis for SDHB-Mutated Pheochromocytoma and Paraganglioma
por: Liu, Yang, et al.
Publicado: (2020)

RNA-Sequencing Analysis of Adrenocortical Carcinoma, Pheochromocytoma and Paraganglioma from a Pan-Cancer Perspective
por: Crona, Joakim, et al.
Publicado: (2018)

MON-199 Targeting Pheochromocytoma/Paraganglioma with Polyamine Inhibitors
por: Ghayee, Hans Kumar, et al.
Publicado: (2020)

Pheochromocytomas and secreting paragangliomas
por: Plouin, Pierre-François, et al.
Publicado: (2006)

Clinical, Diagnostic, and Treatment Characteristics of SDHA-Related Metastatic Pheochromocytoma and Paraganglioma
por: Jha, Abhishek, et al.
Publicado: (2019)

[(18)F]FDG-PET/CT radiomics for the identification of genetic clusters in pheochromocytomas and paragangliomas
por: Noortman, Wyanne A., et al.
Publicado: (2022)

OR29-6 Brown Adipose Tissue Activation in SDHx-Related Pheochromocytoma and Paraganglioma: An Ominous Sign?
por: Abdul Sater, Zahraa, et al.
Publicado: (2019)

SAT-LB311 Inoperable, Metastatic Pheochromocytoma & Paraganglioma Tumor Size Reduction After Lu-177-dotatate (Lutathera®) Treatment Trial: The Role of Nursing
por: Ude, Assumpta, et al.
Publicado: (2020)

Biomarker identification of immune-related genes in pheochromocytoma and paraganglioma
por: Wan, Guang Yang
Publicado: (2023)

Chromogranin A in the Laboratory Diagnosis of Pheochromocytoma and Paraganglioma
por: Bílek, Radovan, et al.
Publicado: (2019)

Optimizing Genetic Workup in Pheochromocytoma and Paraganglioma by Integrating Diagnostic and Research Approaches
por: Gieldon, Laura, et al.
Publicado: (2019)

DLST mutations in pheochromocytoma and paraganglioma cause proteome hyposuccinylation and metabolic remodeling
por: Mellid, Sara, et al.
Publicado: (2023)

Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma
por: Calsina, Bruna, et al.
Publicado: (2023)

Pheochromocytoma and paraganglioma: imaging characteristics
por: Baez, Juan C., et al.
Publicado: (2012)

Glycemic Disturbances in Pheochromocytoma and Paraganglioma
por: Ronen, Joshua A, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_f9u8b4f24h123q86ro110d82ki