Extraskeletal Myxoid Chondrosarcoma Identified in a Traumatic Fracture of the Toe: A Case Report

INTRODUCTION: Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft-tissue sarcoma that typically presents in the proximal lower extremity and limb-girdle. It can be easily misdiagnosed, especially when located in atypical locations like the foot. CASE REPORT: We present the case of an 80-year-old Caucasian female with a left 3rd toe pain and swelling that was initially misdiagnosed as a traumatic fracture on radiographs but later determined to be an indolent EMC based on histology. She was successfully treated with amputation of the toe. CONCLUSION: EMC should be considered in the differential of osseous and soft-tissue abnormalities on radiographic imaging of the extremities. As reported in the literature, it can present in atypical locations with minimal symptoms and successful treatments include resection. Future cases presenting similarly should be evaluated for EMC and, if present, reported along with their applied treatment protocols to allow for further assessment of current therapeutic guidelines.