Variation in histone configurations correlates with gene expression across nine inbred strains of mice

The Diversity Outbred (DO) mice and their inbred founders are widely used models of human disease. However, although the genetic diversity of these mice has been well documented, their epigenetic diversity has not. Epigenetic modifications, such as histone modifications and DNA methylation, are impo...

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Detalles Bibliográficos
Autores principales: Tyler, Anna L., Spruce, Catrina, Kursawe, Romy, Haber, Annat, Ball, Robyn L., Pitman, Wendy A., Fine, Alexander D., Raghupathy, Narayanan, Walker, Michael, Philip, Vivek M., Baker, Christopher L., Mahoney, J. Matthew, Churchill, Gary A., Trowbridge, Jennifer J., Stitzel, Michael L., Paigen, Kenneth, Petkov, Petko M., Carter, Gregory W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519406/
https://www.ncbi.nlm.nih.gov/pubmed/37217254
http://dx.doi.org/10.1101/gr.277467.122

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