Cargando…
Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single-cell resolution
Synthetic glucocorticoids, such as dexamethasone, have been used as a treatment for many immune conditions, such as asthma and, more recently, severe COVID-19. Single-cell data can capture more fine-grained details on transcriptional variability and dynamics to gain a better understanding of the mol...
Autores principales: | Resztak, Justyna A., Wei, Julong, Zilioli, Samuele, Sendler, Edward, Alazizi, Adnan, Mair-Meijers, Henriette E., Wu, Peijun, Wen, Xiaoquan, Slatcher, Richard B., Zhou, Xiang, Luca, Francesca, Pique-Regi, Roger |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519413/ https://www.ncbi.nlm.nih.gov/pubmed/37442575 http://dx.doi.org/10.1101/gr.276765.122 |
Ejemplares similares
-
Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single cell resolution
por: Resztak, Justyna A, et al.
Publicado: (2022) -
Psychosocial experiences modulate asthma-associated genes through gene-environment interactions
por: Resztak, Justyna A, et al.
Publicado: (2021) -
Analysis of transcriptional changes in the immune system associated with pubertal development in a longitudinal cohort of children with asthma
por: Resztak, Justyna A., et al.
Publicado: (2023) -
Interspecies variation in hominid gut microbiota controls host gene regulation
por: Muehlbauer, Amanda L., et al.
Publicado: (2021) -
Single Nucleus Transcriptomics Reveals Pervasive Glial Activation in Opioid Overdose Cases
por: Wei, Julong, et al.
Publicado: (2023)