Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single-cell resolution

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Synthetic glucocorticoids, such as dexamethasone, have been used as a treatment for many immune conditions, such as asthma and, more recently, severe COVID-19. Single-cell data can capture more fine-grained details on transcriptional variability and dynamics to gain a better understanding of the mol...

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Detalles Bibliográficos
Autores principales: Resztak, Justyna A., Wei, Julong, Zilioli, Samuele, Sendler, Edward, Alazizi, Adnan, Mair-Meijers, Henriette E., Wu, Peijun, Wen, Xiaoquan, Slatcher, Richard B., Zhou, Xiang, Luca, Francesca, Pique-Regi, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519413/
https://www.ncbi.nlm.nih.gov/pubmed/37442575
http://dx.doi.org/10.1101/gr.276765.122
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