Cargando…

Study on the active ingredients of Shenghui decoction inhibiting acetylcholinesterase based on molecular docking and molecular dynamics simulation

We aim to investigate the mechanism and effective components of Shenghui decoction (SHD), which has been shown to inhibit acetylcholinesterase (AChE) through molecular docking (MD) and molecular dynamics simulation (MDS). The effective ingredients in SHD were collected through the TCMSP database and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Zefei, Shi, Heyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	4200
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519482/ https://www.ncbi.nlm.nih.gov/pubmed/37746985 http://dx.doi.org/10.1097/MD.0000000000034909

Ejemplares similares

Exploring the active components and mechanism of modified bazhen decoction in treatment of chronic cerebral circulation insufficiency based on network pharmacology and molecular docking
por: Xu, Zhongbo, et al.
Publicado: (2023)

Exploring the molecular mechanism of Nux Vomica in treating ischemic stroke using network pharmacology and molecular docking methods
por: Zhang, Chengdong, et al.
Publicado: (2023)

Analysis of the active components and mechanism of Shufeng Jiedu capsule against COVID-19 based on network pharmacology and molecular docking
por: Simayi, Jimilihan, et al.
Publicado: (2022)

Network pharmacology and molecular docking reveal the mechanism of Angelica dahurica against Osteosarcoma
por: Zhang, Yafang, et al.
Publicado: (2022)

Network pharmacology, molecular docking and bioinformatics reveal the mechanism of Tripterygii Wilfordii against Osteosarcoma
por: Zhang, Yafang, et al.
Publicado: (2022)

Exploring potential mechanisms of Suhexiang Pill against COVID-19 based on network pharmacology and molecular docking
por: Li, Jialin, et al.
Publicado: (2021)

Study on the mechanism of Shujin Tongluo granules in treating cervical spondylosis based on network pharmacology and molecular docking
por: Wang, Yixuan, et al.
Publicado: (2023)

Network pharmacology and molecular docking-based investigation on traditional Chinese medicine Astragalus membranaceus in oral ulcer treatment
por: Zhong, Wan, et al.
Publicado: (2023)

Exploring the mechanism of action of total glucosides of paeony against autoimmune thyroiditis based on network pharmacology and molecular docking
por: Su, Jin, et al.
Publicado: (2023)

Investigating the mechanism of Tongqiao Huoxue decotion in the treatment of allergic rhinitis based on network pharmacology and molecular docking: A review
por: Zhang, Fang, et al.
Publicado: (2023)

The potential mechanism of the Ruhao Dashi formula in treating acute pneumonia via network pharmacology and molecular docking
por: Yi, Xiu-Xiu, et al.
Publicado: (2023)

Network pharmacology-based screening of the active ingredients and mechanisms of Huangqi against aging
por: Lan, Siyu, et al.
Publicado: (2021)

The mechanism of peach kernel and safflower herb-pair for the treatment of liver fibrosis based on network pharmacology and molecular docking technology: A review
por: Huang, Long, et al.
Publicado: (2023)

Network pharmacology integrated with molecular docking technology to reveal the potential mechanism of Shuganfang against drug-induced liver injury
por: Wang, Ying, et al.
Publicado: (2023)

Network pharmacology and molecular docking technology for exploring the effect and mechanism of Radix Bupleuri and Radix Paeoniae Alba herb-pair on anti-hepatitis: A review
por: Huang, Long, et al.
Publicado: (2023)

Inhibition of acetylcholinesterase by two genistein derivatives: kinetic analysis, molecular docking and molecular dynamics simulation
por: Fang, Jiansong, et al.
Publicado: (2014)

Molecular mechanism of oroxyli semen against triple-negative breast cancer verified by bioinformatics and in vitro experiments
por: Chen, Lulu, et al.
Publicado: (2023)

Acetylcholinesterase-Inhibiting Activity of Salicylanilide N-Alkylcarbamates and Their Molecular Docking
por: Imramovsky, Ales, et al.
Publicado: (2012)

The “Warrior” system: a new useful emergency simulator to train clinical pharmacists in emergency medicine
por: Huang, Cong, et al.
Publicado: (2020)

Effect of Jin three needles combined with Tong Qiao and blood activation Tang on neurological function, coagulation function and serum level in stroke patients
por: Xiao, Zhong-Xiang, et al.
Publicado: (2023)

Identification of Potential Herbal Inhibitor of Acetylcholinesterase Associated Alzheimer's Disorders Using Molecular Docking and Molecular Dynamics Simulation
por: Seniya, Chandrabhan, et al.
Publicado: (2014)

Chemical profile of Lippia thymoides, evaluation of the acetylcholinesterase inhibitory activity of its essential oil, and molecular docking and molecular dynamics simulations
por: Silva, Sebastião Gomes, et al.
Publicado: (2019)

Clinical analysis of the effects of azole antifungal agents on the anticoagulant activity of warfarin
por: Chen, Wenjun, et al.
Publicado: (2020)

Platelet inhibitory activity, tolerability, and safety of vicagrel, a novel thienopyridine P2Y12 inhibitor
por: Li, Hui, et al.
Publicado: (2020)

Monitoring of blood immunosuppressant concentrations and lymphocyte activation for predicting viral infections following kidney transplantation: A pilot study
por: Iwamoto, Takuya, et al.
Publicado: (2022)

Hypertonic saline and mannitol in patients with traumatic brain injury: A systematic and meta-analysis
por: Shi, Jiamin, et al.
Publicado: (2020)

Low-Dose Versus Standard-Dose Tissue Plasminogen Activator in Acute Ischemic Stroke in Asian Populations: A Meta-Analysis
por: Liu, Meng-Dong, et al.
Publicado: (2015)

Mast cells activation and high blood tryptase levels due to paclitaxel administration. Is Cremophor EL the culprit?: A case report
por: D’Errico, Stefano, et al.
Publicado: (2020)

Reversible severe fatty liver induced by capecitabine: A case report
por: Jiang, Yiyan, et al.
Publicado: (2017)

Adverse reactions of vancomycin in humans: A protocol for meta-analysis
por: Peng, Yang, et al.
Publicado: (2020)

Polymyxin B-induced rhabdomyolysis: A case report
por: Ni, Ming, et al.
Publicado: (2020)

The application value of operating room ventilation with laminar airflow for surgical site infection: A protocol for a systematic review and meta-analysis
por: Liu, Yuan-Yuan, et al.
Publicado: (2021)

Unfolding the Antibacterial Activity and Acetylcholinesterase Inhibition Potential of Benzofuran-Triazole Hybrids: Synthesis, Antibacterial, Acetylcholinesterase Inhibition, and Molecular Docking Studies
por: Saeed, Sadaf, et al.
Publicado: (2023)

Effect of ertugliflozin on renal function and cardiovascular outcomes in patients with type 2 diabetes mellitus: A systematic review and meta-analysis
por: Cheng, Qian, et al.
Publicado: (2023)

Rituximab was used to treat recurrent IgG4-related hypophysitis with ophthalmopathy as the initial presentation: A case report and literature review
por: Gu, Wei-Jun, et al.
Publicado: (2017)

Drug-induced liver injury in COVID-19 patients during hospitalization
por: Chen, Ying, et al.
Publicado: (2023)

Bisphenol A and Hormone-Associated Cancers: Current Progress and Perspectives
por: Gao, Hui, et al.
Publicado: (2015)

Incidence and non-genetic risk factors of irinotecan-induced severe neutropenia in Chinese adult inpatients
por: Zhang, Shuxiao, et al.
Publicado: (2023)

A novel application of drug-eluting transarterial chemoembolization in treating non-liver cancers
por: Li, Zhen, et al.
Publicado: (2020)

Active ingredients and molecular targets of Taraxacum mongolicum against hepatocellular carcinoma: network pharmacology, molecular docking, and molecular dynamics simulation analysis
por: Zheng, Yanfeng, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rrdndvg3epdo545603mh7bfq9g