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Tertiary Cardiovascular Syphilis Presenting as Aortic Regurgitation, Aortitis, Thrombus, and Coronary Artery Occlusion, Requiring Percutaneous Coronary Intervention

Patient: Male, 51-year-old Final Diagnosis: Syphilis Symptoms: Dyspena Clinical Procedure: — Specialty: Cardiology OBJECTIVE: Rare coexistence of disease or pathology BACKGROUND: Heart failure is caused by coronary artery disease, valvular disease, and arrhythmias and is highly treatable with recent...

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Autores principales: Uehara, Hiroki, Okuyama, Masaki, Oe, Yutaro, Yoshimura, Takaki, Gunji, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519639/
https://www.ncbi.nlm.nih.gov/pubmed/37735866
http://dx.doi.org/10.12659/AJCR.941070
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author Uehara, Hiroki
Okuyama, Masaki
Oe, Yutaro
Yoshimura, Takaki
Gunji, Takahiro
author_facet Uehara, Hiroki
Okuyama, Masaki
Oe, Yutaro
Yoshimura, Takaki
Gunji, Takahiro
author_sort Uehara, Hiroki
collection PubMed
description Patient: Male, 51-year-old Final Diagnosis: Syphilis Symptoms: Dyspena Clinical Procedure: — Specialty: Cardiology OBJECTIVE: Rare coexistence of disease or pathology BACKGROUND: Heart failure is caused by coronary artery disease, valvular disease, and arrhythmias and is highly treatable with recent technology. However, the incidence of syphilis is increasing worldwide. This case report describes tertiary cardiovascular syphilis, accompanied by aortic regurgitation, syphilitic aortitis complicated by thrombus of the ascending aorta, and coronary artery occlusion, requiring percutaneous coronary artery intervention. CASE REPORT: A 51-year-old Japanese man with no significant medical history was admitted to the hospital for worsening shortness of breath on exertion. On physical examination, there was no edema in either lower leg. Chest X-rays showed an enlarged heart and pulmonary congestion, and echocardiography showed a left ventricular ejection fraction of 18%, with full circumferential wall motion impairment. Heart failure was diagnosed, and the patient was found to have severe coronary artery disease and aortic regurgitation. He underwent percutaneous coronary intervention (PCI) for his coronary artery occlusion and was treated with medications for heart failure. Two months later, his condition improved, and PCI was performed for the revascularization of the remaining coronary artery. After PCI was completed, the patient was evaluated for vasculitis. The aortic wall lesion was likely a result of non-active syphilitic aortitis, and the results of serological tests of syphilis were positive. Therefore, we concluded that the diagnosis was cardiovascular syphilis. CONCLUSIONS: This case report has highlighted the need for clinicians to be aware of the cardiovascular findings in syphilis, including syphilitic aortitis, particularly at this time, when the global incidence of syphilis is increasing.
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spelling pubmed-105196392023-09-26 Tertiary Cardiovascular Syphilis Presenting as Aortic Regurgitation, Aortitis, Thrombus, and Coronary Artery Occlusion, Requiring Percutaneous Coronary Intervention Uehara, Hiroki Okuyama, Masaki Oe, Yutaro Yoshimura, Takaki Gunji, Takahiro Am J Case Rep Articles Patient: Male, 51-year-old Final Diagnosis: Syphilis Symptoms: Dyspena Clinical Procedure: — Specialty: Cardiology OBJECTIVE: Rare coexistence of disease or pathology BACKGROUND: Heart failure is caused by coronary artery disease, valvular disease, and arrhythmias and is highly treatable with recent technology. However, the incidence of syphilis is increasing worldwide. This case report describes tertiary cardiovascular syphilis, accompanied by aortic regurgitation, syphilitic aortitis complicated by thrombus of the ascending aorta, and coronary artery occlusion, requiring percutaneous coronary artery intervention. CASE REPORT: A 51-year-old Japanese man with no significant medical history was admitted to the hospital for worsening shortness of breath on exertion. On physical examination, there was no edema in either lower leg. Chest X-rays showed an enlarged heart and pulmonary congestion, and echocardiography showed a left ventricular ejection fraction of 18%, with full circumferential wall motion impairment. Heart failure was diagnosed, and the patient was found to have severe coronary artery disease and aortic regurgitation. He underwent percutaneous coronary intervention (PCI) for his coronary artery occlusion and was treated with medications for heart failure. Two months later, his condition improved, and PCI was performed for the revascularization of the remaining coronary artery. After PCI was completed, the patient was evaluated for vasculitis. The aortic wall lesion was likely a result of non-active syphilitic aortitis, and the results of serological tests of syphilis were positive. Therefore, we concluded that the diagnosis was cardiovascular syphilis. CONCLUSIONS: This case report has highlighted the need for clinicians to be aware of the cardiovascular findings in syphilis, including syphilitic aortitis, particularly at this time, when the global incidence of syphilis is increasing. International Scientific Literature, Inc. 2023-09-22 /pmc/articles/PMC10519639/ /pubmed/37735866 http://dx.doi.org/10.12659/AJCR.941070 Text en © Am J Case Rep, 2023 https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Articles
Uehara, Hiroki
Okuyama, Masaki
Oe, Yutaro
Yoshimura, Takaki
Gunji, Takahiro
Tertiary Cardiovascular Syphilis Presenting as Aortic Regurgitation, Aortitis, Thrombus, and Coronary Artery Occlusion, Requiring Percutaneous Coronary Intervention
title Tertiary Cardiovascular Syphilis Presenting as Aortic Regurgitation, Aortitis, Thrombus, and Coronary Artery Occlusion, Requiring Percutaneous Coronary Intervention
title_full Tertiary Cardiovascular Syphilis Presenting as Aortic Regurgitation, Aortitis, Thrombus, and Coronary Artery Occlusion, Requiring Percutaneous Coronary Intervention
title_fullStr Tertiary Cardiovascular Syphilis Presenting as Aortic Regurgitation, Aortitis, Thrombus, and Coronary Artery Occlusion, Requiring Percutaneous Coronary Intervention
title_full_unstemmed Tertiary Cardiovascular Syphilis Presenting as Aortic Regurgitation, Aortitis, Thrombus, and Coronary Artery Occlusion, Requiring Percutaneous Coronary Intervention
title_short Tertiary Cardiovascular Syphilis Presenting as Aortic Regurgitation, Aortitis, Thrombus, and Coronary Artery Occlusion, Requiring Percutaneous Coronary Intervention
title_sort tertiary cardiovascular syphilis presenting as aortic regurgitation, aortitis, thrombus, and coronary artery occlusion, requiring percutaneous coronary intervention
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519639/
https://www.ncbi.nlm.nih.gov/pubmed/37735866
http://dx.doi.org/10.12659/AJCR.941070
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