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Tertiary Cardiovascular Syphilis Presenting as Aortic Regurgitation, Aortitis, Thrombus, and Coronary Artery Occlusion, Requiring Percutaneous Coronary Intervention
Patient: Male, 51-year-old Final Diagnosis: Syphilis Symptoms: Dyspena Clinical Procedure: — Specialty: Cardiology OBJECTIVE: Rare coexistence of disease or pathology BACKGROUND: Heart failure is caused by coronary artery disease, valvular disease, and arrhythmias and is highly treatable with recent...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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International Scientific Literature, Inc.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519639/ https://www.ncbi.nlm.nih.gov/pubmed/37735866 http://dx.doi.org/10.12659/AJCR.941070 |
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author | Uehara, Hiroki Okuyama, Masaki Oe, Yutaro Yoshimura, Takaki Gunji, Takahiro |
author_facet | Uehara, Hiroki Okuyama, Masaki Oe, Yutaro Yoshimura, Takaki Gunji, Takahiro |
author_sort | Uehara, Hiroki |
collection | PubMed |
description | Patient: Male, 51-year-old Final Diagnosis: Syphilis Symptoms: Dyspena Clinical Procedure: — Specialty: Cardiology OBJECTIVE: Rare coexistence of disease or pathology BACKGROUND: Heart failure is caused by coronary artery disease, valvular disease, and arrhythmias and is highly treatable with recent technology. However, the incidence of syphilis is increasing worldwide. This case report describes tertiary cardiovascular syphilis, accompanied by aortic regurgitation, syphilitic aortitis complicated by thrombus of the ascending aorta, and coronary artery occlusion, requiring percutaneous coronary artery intervention. CASE REPORT: A 51-year-old Japanese man with no significant medical history was admitted to the hospital for worsening shortness of breath on exertion. On physical examination, there was no edema in either lower leg. Chest X-rays showed an enlarged heart and pulmonary congestion, and echocardiography showed a left ventricular ejection fraction of 18%, with full circumferential wall motion impairment. Heart failure was diagnosed, and the patient was found to have severe coronary artery disease and aortic regurgitation. He underwent percutaneous coronary intervention (PCI) for his coronary artery occlusion and was treated with medications for heart failure. Two months later, his condition improved, and PCI was performed for the revascularization of the remaining coronary artery. After PCI was completed, the patient was evaluated for vasculitis. The aortic wall lesion was likely a result of non-active syphilitic aortitis, and the results of serological tests of syphilis were positive. Therefore, we concluded that the diagnosis was cardiovascular syphilis. CONCLUSIONS: This case report has highlighted the need for clinicians to be aware of the cardiovascular findings in syphilis, including syphilitic aortitis, particularly at this time, when the global incidence of syphilis is increasing. |
format | Online Article Text |
id | pubmed-10519639 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | International Scientific Literature, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-105196392023-09-26 Tertiary Cardiovascular Syphilis Presenting as Aortic Regurgitation, Aortitis, Thrombus, and Coronary Artery Occlusion, Requiring Percutaneous Coronary Intervention Uehara, Hiroki Okuyama, Masaki Oe, Yutaro Yoshimura, Takaki Gunji, Takahiro Am J Case Rep Articles Patient: Male, 51-year-old Final Diagnosis: Syphilis Symptoms: Dyspena Clinical Procedure: — Specialty: Cardiology OBJECTIVE: Rare coexistence of disease or pathology BACKGROUND: Heart failure is caused by coronary artery disease, valvular disease, and arrhythmias and is highly treatable with recent technology. However, the incidence of syphilis is increasing worldwide. This case report describes tertiary cardiovascular syphilis, accompanied by aortic regurgitation, syphilitic aortitis complicated by thrombus of the ascending aorta, and coronary artery occlusion, requiring percutaneous coronary artery intervention. CASE REPORT: A 51-year-old Japanese man with no significant medical history was admitted to the hospital for worsening shortness of breath on exertion. On physical examination, there was no edema in either lower leg. Chest X-rays showed an enlarged heart and pulmonary congestion, and echocardiography showed a left ventricular ejection fraction of 18%, with full circumferential wall motion impairment. Heart failure was diagnosed, and the patient was found to have severe coronary artery disease and aortic regurgitation. He underwent percutaneous coronary intervention (PCI) for his coronary artery occlusion and was treated with medications for heart failure. Two months later, his condition improved, and PCI was performed for the revascularization of the remaining coronary artery. After PCI was completed, the patient was evaluated for vasculitis. The aortic wall lesion was likely a result of non-active syphilitic aortitis, and the results of serological tests of syphilis were positive. Therefore, we concluded that the diagnosis was cardiovascular syphilis. CONCLUSIONS: This case report has highlighted the need for clinicians to be aware of the cardiovascular findings in syphilis, including syphilitic aortitis, particularly at this time, when the global incidence of syphilis is increasing. International Scientific Literature, Inc. 2023-09-22 /pmc/articles/PMC10519639/ /pubmed/37735866 http://dx.doi.org/10.12659/AJCR.941070 Text en © Am J Case Rep, 2023 https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) ) |
spellingShingle | Articles Uehara, Hiroki Okuyama, Masaki Oe, Yutaro Yoshimura, Takaki Gunji, Takahiro Tertiary Cardiovascular Syphilis Presenting as Aortic Regurgitation, Aortitis, Thrombus, and Coronary Artery Occlusion, Requiring Percutaneous Coronary Intervention |
title | Tertiary Cardiovascular Syphilis Presenting as Aortic Regurgitation, Aortitis, Thrombus, and Coronary Artery Occlusion, Requiring Percutaneous Coronary Intervention |
title_full | Tertiary Cardiovascular Syphilis Presenting as Aortic Regurgitation, Aortitis, Thrombus, and Coronary Artery Occlusion, Requiring Percutaneous Coronary Intervention |
title_fullStr | Tertiary Cardiovascular Syphilis Presenting as Aortic Regurgitation, Aortitis, Thrombus, and Coronary Artery Occlusion, Requiring Percutaneous Coronary Intervention |
title_full_unstemmed | Tertiary Cardiovascular Syphilis Presenting as Aortic Regurgitation, Aortitis, Thrombus, and Coronary Artery Occlusion, Requiring Percutaneous Coronary Intervention |
title_short | Tertiary Cardiovascular Syphilis Presenting as Aortic Regurgitation, Aortitis, Thrombus, and Coronary Artery Occlusion, Requiring Percutaneous Coronary Intervention |
title_sort | tertiary cardiovascular syphilis presenting as aortic regurgitation, aortitis, thrombus, and coronary artery occlusion, requiring percutaneous coronary intervention |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519639/ https://www.ncbi.nlm.nih.gov/pubmed/37735866 http://dx.doi.org/10.12659/AJCR.941070 |
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