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Treatment of drop attacks: Anti-seizure drug choices of pediatric neurologists in Saudi Arabia

OBJECTIVES: To evaluate Epileptic drop attacks (EDAs) treatment options among pediatric neurologists in Saudi Arabia (SA) and to develop a recommendation scheme for the management of EDAs in SA. Epileptic drop attacks are one of the most pharmaco-resistant epileptic seizures. The different approache...

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Autores principales: Alhiniah, Mudhawi, Alshahrani, Asma, Rajab, Renad, Alelyani, Rakan, Badawi, Atheer, Abbar, Abrar, Abdulsbhan, Mashael, Alrajhi, Amir, Muthaffar, Osama, Jan, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Riyadh : Armed Forces Hospital 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519658/
https://www.ncbi.nlm.nih.gov/pubmed/37482388
http://dx.doi.org/10.17712/nsj.2023.3.20230008
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author Alhiniah, Mudhawi
Alshahrani, Asma
Rajab, Renad
Alelyani, Rakan
Badawi, Atheer
Abbar, Abrar
Abdulsbhan, Mashael
Alrajhi, Amir
Muthaffar, Osama
Jan, Mohammed
author_facet Alhiniah, Mudhawi
Alshahrani, Asma
Rajab, Renad
Alelyani, Rakan
Badawi, Atheer
Abbar, Abrar
Abdulsbhan, Mashael
Alrajhi, Amir
Muthaffar, Osama
Jan, Mohammed
author_sort Alhiniah, Mudhawi
collection PubMed
description OBJECTIVES: To evaluate Epileptic drop attacks (EDAs) treatment options among pediatric neurologists in Saudi Arabia (SA) and to develop a recommendation scheme for the management of EDAs in SA. Epileptic drop attacks are one of the most pharmaco-resistant epileptic seizures. The different approaches to EDA treatment are influenced by a variety of factors, including pharmaceutical availability, costs, side effects, treating physicians’ experience and personal preferences. METHODS: This cross-sectional study was conducted online. A structured questionnaire that aimed to measure the therapeutic options for patients with EDA was electronically distributed to pediatric neurologists across SA. It contained 21 questions, and the data were collected in Excel sheets and analyzed. RESULTS: Our study included a cohort of 71 pediatric neurologists from SA, of which male doctors represented 60%. Most of the participating pediatric neurologists had more than 10 years of experience in the field. We found that 77% of the included pediatric neurologists used valproic acid as a first-line drug in patients with EDA. Further, in the different case scenarios provided to participants, levetiracetam, clobazam, topiramate, and rufinamide were included in the initial management protocol for EDA. CONCLUSION: The majority of pediatric neurologists in Saudi Arabia chose valproic acid and/or levetiracetam as the first line of treatment for EDA. These results highlight the need for an evidence-based clinical guidelines to treat EDA.
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spelling pubmed-105196582023-09-26 Treatment of drop attacks: Anti-seizure drug choices of pediatric neurologists in Saudi Arabia Alhiniah, Mudhawi Alshahrani, Asma Rajab, Renad Alelyani, Rakan Badawi, Atheer Abbar, Abrar Abdulsbhan, Mashael Alrajhi, Amir Muthaffar, Osama Jan, Mohammed Neurosciences (Riyadh) Original Article OBJECTIVES: To evaluate Epileptic drop attacks (EDAs) treatment options among pediatric neurologists in Saudi Arabia (SA) and to develop a recommendation scheme for the management of EDAs in SA. Epileptic drop attacks are one of the most pharmaco-resistant epileptic seizures. The different approaches to EDA treatment are influenced by a variety of factors, including pharmaceutical availability, costs, side effects, treating physicians’ experience and personal preferences. METHODS: This cross-sectional study was conducted online. A structured questionnaire that aimed to measure the therapeutic options for patients with EDA was electronically distributed to pediatric neurologists across SA. It contained 21 questions, and the data were collected in Excel sheets and analyzed. RESULTS: Our study included a cohort of 71 pediatric neurologists from SA, of which male doctors represented 60%. Most of the participating pediatric neurologists had more than 10 years of experience in the field. We found that 77% of the included pediatric neurologists used valproic acid as a first-line drug in patients with EDA. Further, in the different case scenarios provided to participants, levetiracetam, clobazam, topiramate, and rufinamide were included in the initial management protocol for EDA. CONCLUSION: The majority of pediatric neurologists in Saudi Arabia chose valproic acid and/or levetiracetam as the first line of treatment for EDA. These results highlight the need for an evidence-based clinical guidelines to treat EDA. Riyadh : Armed Forces Hospital 2023-07 /pmc/articles/PMC10519658/ /pubmed/37482388 http://dx.doi.org/10.17712/nsj.2023.3.20230008 Text en Copyright: © Neurosciences https://creativecommons.org/licenses/by-nc/3.0/Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.
spellingShingle Original Article
Alhiniah, Mudhawi
Alshahrani, Asma
Rajab, Renad
Alelyani, Rakan
Badawi, Atheer
Abbar, Abrar
Abdulsbhan, Mashael
Alrajhi, Amir
Muthaffar, Osama
Jan, Mohammed
Treatment of drop attacks: Anti-seizure drug choices of pediatric neurologists in Saudi Arabia
title Treatment of drop attacks: Anti-seizure drug choices of pediatric neurologists in Saudi Arabia
title_full Treatment of drop attacks: Anti-seizure drug choices of pediatric neurologists in Saudi Arabia
title_fullStr Treatment of drop attacks: Anti-seizure drug choices of pediatric neurologists in Saudi Arabia
title_full_unstemmed Treatment of drop attacks: Anti-seizure drug choices of pediatric neurologists in Saudi Arabia
title_short Treatment of drop attacks: Anti-seizure drug choices of pediatric neurologists in Saudi Arabia
title_sort treatment of drop attacks: anti-seizure drug choices of pediatric neurologists in saudi arabia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519658/
https://www.ncbi.nlm.nih.gov/pubmed/37482388
http://dx.doi.org/10.17712/nsj.2023.3.20230008
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