Cargando…
Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis
Impaired spermatogenesis and male infertility are common manifestations associated with mitochondrial diseases, yet the underlying mechanisms linking these conditions remain elusive. In this study, we demonstrate that mice deficient for the mitochondrial intra-membrane rhomboid protease PARL, a rece...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519710/ https://www.ncbi.nlm.nih.gov/pubmed/37505079 http://dx.doi.org/10.7554/eLife.84710 |