Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid‐twenties

The Twins Early Development Study (TEDS) is a longitudinal study following a cohort of twins born 1994–1996 in England and Wales. Of the 13,759 families who originally consented to take part, over 10,000 families remain enrolled in the study. The current focus of TEDS is on mental health in the mid‐...

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Autores principales: Lockhart, Celestine, Bright, Joanna, Ahmadzadeh, Yasmin, Breen, Gerome, Bristow, Shannon, Boyd, Andy, Downs, Johnny, Hotopf, Matthew, Palaiologou, Elisavet, Rimfeld, Kaili, Maxwell, Jessye, Malanchini, Margherita, McAdams, Tom A., McMillan, Andrew, Plomin, Robert, Eley, Thalia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Methodological Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519737/
https://www.ncbi.nlm.nih.gov/pubmed/37753150
http://dx.doi.org/10.1002/jcv2.12154
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author Lockhart, Celestine
Bright, Joanna
Ahmadzadeh, Yasmin
Breen, Gerome
Bristow, Shannon
Boyd, Andy
Downs, Johnny
Hotopf, Matthew
Palaiologou, Elisavet
Rimfeld, Kaili
Maxwell, Jessye
Malanchini, Margherita
McAdams, Tom A.
McMillan, Andrew
Plomin, Robert
Eley, Thalia C.
author_facet Lockhart, Celestine
Bright, Joanna
Ahmadzadeh, Yasmin
Breen, Gerome
Bristow, Shannon
Boyd, Andy
Downs, Johnny
Hotopf, Matthew
Palaiologou, Elisavet
Rimfeld, Kaili
Maxwell, Jessye
Malanchini, Margherita
McAdams, Tom A.
McMillan, Andrew
Plomin, Robert
Eley, Thalia C.
author_sort Lockhart, Celestine
collection PubMed
description The Twins Early Development Study (TEDS) is a longitudinal study following a cohort of twins born 1994–1996 in England and Wales. Of the 13,759 families who originally consented to take part, over 10,000 families remain enrolled in the study. The current focus of TEDS is on mental health in the mid‐twenties. Making use of over 25 years of genetically sensitive data, TEDS is uniquely placed to explore the longitudinal genetic and environmental influences on common mental health disorders in early adulthood. This paper outlines recent data collection efforts supporting this work, including a cohort‐wide mental health assessment at age 26 and a multi‐phase Covid‐19 study. It will also provide an update on data linkage efforts and the Children of TEDS (CoTEDS) project.
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spelling pubmed-105197372023-09-26 Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid‐twenties Lockhart, Celestine Bright, Joanna Ahmadzadeh, Yasmin Breen, Gerome Bristow, Shannon Boyd, Andy Downs, Johnny Hotopf, Matthew Palaiologou, Elisavet Rimfeld, Kaili Maxwell, Jessye Malanchini, Margherita McAdams, Tom A. McMillan, Andrew Plomin, Robert Eley, Thalia C. JCPP Adv Methodological Review The Twins Early Development Study (TEDS) is a longitudinal study following a cohort of twins born 1994–1996 in England and Wales. Of the 13,759 families who originally consented to take part, over 10,000 families remain enrolled in the study. The current focus of TEDS is on mental health in the mid‐twenties. Making use of over 25 years of genetically sensitive data, TEDS is uniquely placed to explore the longitudinal genetic and environmental influences on common mental health disorders in early adulthood. This paper outlines recent data collection efforts supporting this work, including a cohort‐wide mental health assessment at age 26 and a multi‐phase Covid‐19 study. It will also provide an update on data linkage efforts and the Children of TEDS (CoTEDS) project. John Wiley and Sons Inc. 2023-03-30 /pmc/articles/PMC10519737/ /pubmed/37753150 http://dx.doi.org/10.1002/jcv2.12154 Text en © 2023 The Authors. JCPP Advances published by John Wiley & Sons Ltd on behalf of Association for Child and Adolescent Mental Health. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Methodological Review
Lockhart, Celestine
Bright, Joanna
Ahmadzadeh, Yasmin
Breen, Gerome
Bristow, Shannon
Boyd, Andy
Downs, Johnny
Hotopf, Matthew
Palaiologou, Elisavet
Rimfeld, Kaili
Maxwell, Jessye
Malanchini, Margherita
McAdams, Tom A.
McMillan, Andrew
Plomin, Robert
Eley, Thalia C.
Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid‐twenties
title Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid‐twenties
title_full Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid‐twenties
title_fullStr Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid‐twenties
title_full_unstemmed Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid‐twenties
title_short Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid‐twenties
title_sort twins early development study (teds): a genetically sensitive investigation of mental health outcomes in the mid‐twenties
topic Methodological Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519737/
https://www.ncbi.nlm.nih.gov/pubmed/37753150
http://dx.doi.org/10.1002/jcv2.12154
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