In Vitro Comparison of Ulotaront (SEP-363856) and Ralmitaront (RO6889450): Two TAAR1 Agonist Candidate Antipsychotics

BACKGROUND: Trace amine-associated receptor-1 (TAAR1) agonists have been proposed as potential antipsychotics, with ulotaront and ralmitaront having reached clinical trials. While ulotaront demonstrated efficacy in a recent Phase II trial, a corresponding study studies of ralmitaront failed to show...

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Detalles Bibliográficos
Autores principales: Ågren, Richard, Betari, Nibal, Saarinen, Marcus, Zeberg, Hugo, Svenningsson, Per, Sahlholm, Kristoffer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519813/
https://www.ncbi.nlm.nih.gov/pubmed/37549917
http://dx.doi.org/10.1093/ijnp/pyad049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519813/
https://www.ncbi.nlm.nih.gov/pubmed/37549917
http://dx.doi.org/10.1093/ijnp/pyad049

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