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The matrix microenvironment influences but does not dominate tissue-specific stem cell lineage differentiation
Mesenchymal stem cells (MSCs) play a pivotal role in tissue engineering and regenerative medicine, with their clinical application often hindered by cell senescence during ex vivo expansion. Recent studies suggest that MSC-deposited decellularized extracellular matrix (dECM) offers a conducive micro...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519827/ https://www.ncbi.nlm.nih.gov/pubmed/37766896 http://dx.doi.org/10.1016/j.mtbio.2023.100805 |