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Metabolic reprogramming contributes to radioprotection by protein kinase Cδ
Loss of protein kinase Cδ (PKCδ) activity renders cells resistant to DNA damaging agents, including irradiation; however, the mechanism(s) underlying resistance is poorly understood. Here, we have asked if metabolic reprogramming by PKCδ contributes to radioprotection. Analysis of global metabolomic...
Autores principales: | Ohm, Angela M., Affandi, Trisiani, Reisz, Julie A., Caino, M. Cecilia, D’Alessandro, Angelo, Reyland, Mary E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519828/ https://www.ncbi.nlm.nih.gov/pubmed/37611829 http://dx.doi.org/10.1016/j.jbc.2023.105186 |
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