Cargando…

Peptides as carriers of active ingredients: A review

Bioactive compounds are highly valuable in the fields of food and medicine, but their application is limited due to easy deterioration after oral or skin administration. In recent years, the use of peptides as delivery systems for bioactive compounds has been intensively researched because of their...

Descripción completa

Detalles Bibliográficos
Autores principales: Nie, Congyi, Zou, Yuxiao, Liao, Sentai, Gao, Qunyu, Li, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519830/
https://www.ncbi.nlm.nih.gov/pubmed/37766891
http://dx.doi.org/10.1016/j.crfs.2023.100592
_version_ 1785109779904987136
author Nie, Congyi
Zou, Yuxiao
Liao, Sentai
Gao, Qunyu
Li, Qian
author_facet Nie, Congyi
Zou, Yuxiao
Liao, Sentai
Gao, Qunyu
Li, Qian
author_sort Nie, Congyi
collection PubMed
description Bioactive compounds are highly valuable in the fields of food and medicine, but their application is limited due to easy deterioration after oral or skin administration. In recent years, the use of peptides as delivery systems for bioactive compounds has been intensively researched because of their special physicochemical characteristics. Peptides can be assembled using various preparation methods and can form several composite materials such as hydrogels, micelles, emulsions and particles. The composite material properties are determined by peptides, bioactive compounds and the construction methods employed. Herein, this paper provides a comprehensive review of the peptides used for active ingredients delivery, fabrication methods for creating delivery systems, structures, targeting characteristics, functional activities and mechanism of delivery systems, as well as their absorption and metabolism, which provided theoretical basis and reference for further research and development of functional composites.
format Online
Article
Text
id pubmed-10519830
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-105198302023-09-27 Peptides as carriers of active ingredients: A review Nie, Congyi Zou, Yuxiao Liao, Sentai Gao, Qunyu Li, Qian Curr Res Food Sci Review Article Bioactive compounds are highly valuable in the fields of food and medicine, but their application is limited due to easy deterioration after oral or skin administration. In recent years, the use of peptides as delivery systems for bioactive compounds has been intensively researched because of their special physicochemical characteristics. Peptides can be assembled using various preparation methods and can form several composite materials such as hydrogels, micelles, emulsions and particles. The composite material properties are determined by peptides, bioactive compounds and the construction methods employed. Herein, this paper provides a comprehensive review of the peptides used for active ingredients delivery, fabrication methods for creating delivery systems, structures, targeting characteristics, functional activities and mechanism of delivery systems, as well as their absorption and metabolism, which provided theoretical basis and reference for further research and development of functional composites. Elsevier 2023-09-17 /pmc/articles/PMC10519830/ /pubmed/37766891 http://dx.doi.org/10.1016/j.crfs.2023.100592 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Nie, Congyi
Zou, Yuxiao
Liao, Sentai
Gao, Qunyu
Li, Qian
Peptides as carriers of active ingredients: A review
title Peptides as carriers of active ingredients: A review
title_full Peptides as carriers of active ingredients: A review
title_fullStr Peptides as carriers of active ingredients: A review
title_full_unstemmed Peptides as carriers of active ingredients: A review
title_short Peptides as carriers of active ingredients: A review
title_sort peptides as carriers of active ingredients: a review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519830/
https://www.ncbi.nlm.nih.gov/pubmed/37766891
http://dx.doi.org/10.1016/j.crfs.2023.100592
work_keys_str_mv AT niecongyi peptidesascarriersofactiveingredientsareview
AT zouyuxiao peptidesascarriersofactiveingredientsareview
AT liaosentai peptidesascarriersofactiveingredientsareview
AT gaoqunyu peptidesascarriersofactiveingredientsareview
AT liqian peptidesascarriersofactiveingredientsareview