Cargando…
Peptides as carriers of active ingredients: A review
Bioactive compounds are highly valuable in the fields of food and medicine, but their application is limited due to easy deterioration after oral or skin administration. In recent years, the use of peptides as delivery systems for bioactive compounds has been intensively researched because of their...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519830/ https://www.ncbi.nlm.nih.gov/pubmed/37766891 http://dx.doi.org/10.1016/j.crfs.2023.100592 |
_version_ | 1785109779904987136 |
---|---|
author | Nie, Congyi Zou, Yuxiao Liao, Sentai Gao, Qunyu Li, Qian |
author_facet | Nie, Congyi Zou, Yuxiao Liao, Sentai Gao, Qunyu Li, Qian |
author_sort | Nie, Congyi |
collection | PubMed |
description | Bioactive compounds are highly valuable in the fields of food and medicine, but their application is limited due to easy deterioration after oral or skin administration. In recent years, the use of peptides as delivery systems for bioactive compounds has been intensively researched because of their special physicochemical characteristics. Peptides can be assembled using various preparation methods and can form several composite materials such as hydrogels, micelles, emulsions and particles. The composite material properties are determined by peptides, bioactive compounds and the construction methods employed. Herein, this paper provides a comprehensive review of the peptides used for active ingredients delivery, fabrication methods for creating delivery systems, structures, targeting characteristics, functional activities and mechanism of delivery systems, as well as their absorption and metabolism, which provided theoretical basis and reference for further research and development of functional composites. |
format | Online Article Text |
id | pubmed-10519830 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-105198302023-09-27 Peptides as carriers of active ingredients: A review Nie, Congyi Zou, Yuxiao Liao, Sentai Gao, Qunyu Li, Qian Curr Res Food Sci Review Article Bioactive compounds are highly valuable in the fields of food and medicine, but their application is limited due to easy deterioration after oral or skin administration. In recent years, the use of peptides as delivery systems for bioactive compounds has been intensively researched because of their special physicochemical characteristics. Peptides can be assembled using various preparation methods and can form several composite materials such as hydrogels, micelles, emulsions and particles. The composite material properties are determined by peptides, bioactive compounds and the construction methods employed. Herein, this paper provides a comprehensive review of the peptides used for active ingredients delivery, fabrication methods for creating delivery systems, structures, targeting characteristics, functional activities and mechanism of delivery systems, as well as their absorption and metabolism, which provided theoretical basis and reference for further research and development of functional composites. Elsevier 2023-09-17 /pmc/articles/PMC10519830/ /pubmed/37766891 http://dx.doi.org/10.1016/j.crfs.2023.100592 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Nie, Congyi Zou, Yuxiao Liao, Sentai Gao, Qunyu Li, Qian Peptides as carriers of active ingredients: A review |
title | Peptides as carriers of active ingredients: A review |
title_full | Peptides as carriers of active ingredients: A review |
title_fullStr | Peptides as carriers of active ingredients: A review |
title_full_unstemmed | Peptides as carriers of active ingredients: A review |
title_short | Peptides as carriers of active ingredients: A review |
title_sort | peptides as carriers of active ingredients: a review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519830/ https://www.ncbi.nlm.nih.gov/pubmed/37766891 http://dx.doi.org/10.1016/j.crfs.2023.100592 |
work_keys_str_mv | AT niecongyi peptidesascarriersofactiveingredientsareview AT zouyuxiao peptidesascarriersofactiveingredientsareview AT liaosentai peptidesascarriersofactiveingredientsareview AT gaoqunyu peptidesascarriersofactiveingredientsareview AT liqian peptidesascarriersofactiveingredientsareview |