Myo9b mutations are associated with altered dendritic cell functions and increased susceptibility to autoimmune diabetes onset

The regulation of autoimmunity against pancreatic islet β cells for type 1 diabetes (T1D) onset is still unclear. NOD/ShiLtJ (NOD) mice are prone to the onset of autoimmune diabetes, but its congenic strain, ALR/Lt (ALR), is not. Here we show that dendritic cells (DC) in ALR mice have impaired migra...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Zou, Yuan, Chen, Longmin, Sun, Fei, Xu, Qianqian, Zhou, Qing, Wang, Yi, Luo, Xi, Wang, Na, Li, Yang, Zhang, Shu, Xiong, Fei, Yang, Ping, Liu, Shiwei, Yang, Tao, Weng, Jianping, Eizirik, Décio L., Yan, Jinhua, Zhou, Zhiguang, Wang, Cong-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519942/
https://www.ncbi.nlm.nih.gov/pubmed/37749140
http://dx.doi.org/10.1038/s41467-023-41534-w

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