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Inflammasome activation occurs in CD4(+) and CD8(+) T cells during graft-versus-host disease

A severe complication of hematopoietic stem cell transplantation is graft-versus-host disease (GvHD), a reaction that occurs following the transfer of donor immune cells (the graft) into an allogeneic host. Transplanted cells recognize host alloantigens as foreign, resulting in the activation of don...

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Detalles Bibliográficos
Autores principales: Talley, Sarah, Rademacher, David J., Campbell, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519954/
https://www.ncbi.nlm.nih.gov/pubmed/37749127
http://dx.doi.org/10.1038/s41419-023-06138-8