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Structural insights into the mechanism of GTP initiation of microtubule assembly

In eukaryotes, the dynamic assembly of microtubules (MT) plays an important role in numerous cellular processes. The underlying mechanism of GTP triggering MT assembly is still unknown. Here, we present cryo-EM structures of tubulin heterodimer at their GTP- and GDP-bound states, intermediate assemb...

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Detalles Bibliográficos
Autores principales:	Zhou, Ju, Wang, Anhui, Song, Yinlong, Liu, Nan, Wang, Jia, Li, Yan, Liang, Xin, Li, Guohui, Chu, Huiying, Wang, Hong-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10519996/ https://www.ncbi.nlm.nih.gov/pubmed/37749104 http://dx.doi.org/10.1038/s41467-023-41615-w

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