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Prognostic factors for lung transplant recipients focusing on age and gender: the Japanese lung transplantation report 2022

PURPOSE: To clarify the impact of donor and recipient characteristics on the survival of recipients before and after lung transplantation in the Japanese population. METHODS: Patients’ data were collected for retrospective analysis from all authorized lung transplant centers in Japan. We included 19...

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Autores principales: Oishi, Hisashi, Okada, Yoshinori, Sato, Masaaki, Nakajima, Jun, Nakajima, Daisuke, Shiraishi, Takeshi, Sato, Toshihiko, Kanou, Takashi, Shintani, Yasushi, Miyoshi, Kentaroh, Toyooka, Shinichi, Maeda, Sumiko, Chida, Masayuki, Matsumoto, Keitaro, Nagayasu, Takeshi, Suzuki, Hidemi, Yoshino, Ichiro, Matsuda, Yasushi, Hoshikawa, Yasushi, Date, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520150/
https://www.ncbi.nlm.nih.gov/pubmed/37074401
http://dx.doi.org/10.1007/s00595-023-02686-w
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author Oishi, Hisashi
Okada, Yoshinori
Sato, Masaaki
Nakajima, Jun
Nakajima, Daisuke
Shiraishi, Takeshi
Sato, Toshihiko
Kanou, Takashi
Shintani, Yasushi
Miyoshi, Kentaroh
Toyooka, Shinichi
Maeda, Sumiko
Chida, Masayuki
Matsumoto, Keitaro
Nagayasu, Takeshi
Suzuki, Hidemi
Yoshino, Ichiro
Matsuda, Yasushi
Hoshikawa, Yasushi
Date, Hiroshi
author_facet Oishi, Hisashi
Okada, Yoshinori
Sato, Masaaki
Nakajima, Jun
Nakajima, Daisuke
Shiraishi, Takeshi
Sato, Toshihiko
Kanou, Takashi
Shintani, Yasushi
Miyoshi, Kentaroh
Toyooka, Shinichi
Maeda, Sumiko
Chida, Masayuki
Matsumoto, Keitaro
Nagayasu, Takeshi
Suzuki, Hidemi
Yoshino, Ichiro
Matsuda, Yasushi
Hoshikawa, Yasushi
Date, Hiroshi
author_sort Oishi, Hisashi
collection PubMed
description PURPOSE: To clarify the impact of donor and recipient characteristics on the survival of recipients before and after lung transplantation in the Japanese population. METHODS: Patients’ data were collected for retrospective analysis from all authorized lung transplant centers in Japan. We included 1963 patients listed for lung transplantation by the end of December 2021, comprised of 658 deceased-donor and 270 living-donor lung transplants. RESULTS: Primary disease had a significant impact on the mortality of patients waiting for transplantation. The indications for transplant significantly affected the post-transplant survival rate of deceased-donor lung transplant recipients. The recipient’s age also significantly affected the post-transplant survival rate of the deceased-donor and living-donor lung transplant recipients. The recipients of grafts transplanted from donors aged 61 years or older showed a worse post-transplant survival rate (≧60 years old). The survival rate for the combination of a female donor to a male recipient among the deceased-donor lung transplant recipients was the worst among the four combinations. CONCLUSION: The donor and recipient characteristics significantly impacted the survival of recipients after lung transplantation. The underlying mechanism of the negative impact of the gender mismatch of female donor to male recipient on post-transplant survival needs to be investigated further.
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spelling pubmed-105201502023-09-27 Prognostic factors for lung transplant recipients focusing on age and gender: the Japanese lung transplantation report 2022 Oishi, Hisashi Okada, Yoshinori Sato, Masaaki Nakajima, Jun Nakajima, Daisuke Shiraishi, Takeshi Sato, Toshihiko Kanou, Takashi Shintani, Yasushi Miyoshi, Kentaroh Toyooka, Shinichi Maeda, Sumiko Chida, Masayuki Matsumoto, Keitaro Nagayasu, Takeshi Suzuki, Hidemi Yoshino, Ichiro Matsuda, Yasushi Hoshikawa, Yasushi Date, Hiroshi Surg Today Original Article PURPOSE: To clarify the impact of donor and recipient characteristics on the survival of recipients before and after lung transplantation in the Japanese population. METHODS: Patients’ data were collected for retrospective analysis from all authorized lung transplant centers in Japan. We included 1963 patients listed for lung transplantation by the end of December 2021, comprised of 658 deceased-donor and 270 living-donor lung transplants. RESULTS: Primary disease had a significant impact on the mortality of patients waiting for transplantation. The indications for transplant significantly affected the post-transplant survival rate of deceased-donor lung transplant recipients. The recipient’s age also significantly affected the post-transplant survival rate of the deceased-donor and living-donor lung transplant recipients. The recipients of grafts transplanted from donors aged 61 years or older showed a worse post-transplant survival rate (≧60 years old). The survival rate for the combination of a female donor to a male recipient among the deceased-donor lung transplant recipients was the worst among the four combinations. CONCLUSION: The donor and recipient characteristics significantly impacted the survival of recipients after lung transplantation. The underlying mechanism of the negative impact of the gender mismatch of female donor to male recipient on post-transplant survival needs to be investigated further. Springer Nature Singapore 2023-04-19 2023 /pmc/articles/PMC10520150/ /pubmed/37074401 http://dx.doi.org/10.1007/s00595-023-02686-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Oishi, Hisashi
Okada, Yoshinori
Sato, Masaaki
Nakajima, Jun
Nakajima, Daisuke
Shiraishi, Takeshi
Sato, Toshihiko
Kanou, Takashi
Shintani, Yasushi
Miyoshi, Kentaroh
Toyooka, Shinichi
Maeda, Sumiko
Chida, Masayuki
Matsumoto, Keitaro
Nagayasu, Takeshi
Suzuki, Hidemi
Yoshino, Ichiro
Matsuda, Yasushi
Hoshikawa, Yasushi
Date, Hiroshi
Prognostic factors for lung transplant recipients focusing on age and gender: the Japanese lung transplantation report 2022
title Prognostic factors for lung transplant recipients focusing on age and gender: the Japanese lung transplantation report 2022
title_full Prognostic factors for lung transplant recipients focusing on age and gender: the Japanese lung transplantation report 2022
title_fullStr Prognostic factors for lung transplant recipients focusing on age and gender: the Japanese lung transplantation report 2022
title_full_unstemmed Prognostic factors for lung transplant recipients focusing on age and gender: the Japanese lung transplantation report 2022
title_short Prognostic factors for lung transplant recipients focusing on age and gender: the Japanese lung transplantation report 2022
title_sort prognostic factors for lung transplant recipients focusing on age and gender: the japanese lung transplantation report 2022
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520150/
https://www.ncbi.nlm.nih.gov/pubmed/37074401
http://dx.doi.org/10.1007/s00595-023-02686-w
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