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Correlation of frailty assessment metrics in one-year follow-up of aged care residents: a sub-study of a randomised controlled trial
INTRODUCTION: Frailty is increasingly recognised as a dynamic syndrome, with multiple causes, dimensions and consequences. There is little understanding of how those frailty assessment metrics interact over time. The aim of this study was to describe the longitudinal correlation between five frailty...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520153/ https://www.ncbi.nlm.nih.gov/pubmed/37452224 http://dx.doi.org/10.1007/s40520-023-02491-y |
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author | Andrade, A. Q. Widagdo, I. Lim, R. Kelly, T.-L. Parfitt, G. Pratt, N. Bilton, R. L. Roughead, E. E. |
author_facet | Andrade, A. Q. Widagdo, I. Lim, R. Kelly, T.-L. Parfitt, G. Pratt, N. Bilton, R. L. Roughead, E. E. |
author_sort | Andrade, A. Q. |
collection | PubMed |
description | INTRODUCTION: Frailty is increasingly recognised as a dynamic syndrome, with multiple causes, dimensions and consequences. There is little understanding of how those frailty assessment metrics interact over time. The aim of this study was to describe the longitudinal correlation between five frailty metrics, namely multimorbidity, muscular strength, mood alterations, cognitive capacity, and functional capacity in a cohort study of aged care (nursing home) residents. METHODS: 248 aged care residents with Frailty Index at baseline of < 0.4 and no dementia were followed for 12 months. A multimorbidity score and an activity of daily living limitation score were created using individual items of the Frailty Index. Muscular strength was measured by grip strength. Cognitive capacity was measured using the Montreal Cognitive Assessment (MoCA) test. Mood alterations were measured using the anxiety/depression screening question from EQ-5D. We analysed the inter-individual correlation at baseline, association between baseline and future change, and within-individual correlation at baseline, 6 and 12 months. RESULTS: Population analysis shows that metrics were not associated at baseline. All of the studied metrics at baseline were associated with change in 12 months, with the exception of anxiety/depression scores. Pairwise within-individual correlation was strong between MoCA and grip strength (0.13, p = 0.02) and activity of daily living (− 0.48, p < 0.001), and between activities of daily living and multimorbidity index (0.28, p < 0.001). No within-individual correlation was found between anxiety depression score and other metrics. CONCLUSION: The results suggest an interdependence between comorbidities, physical capacity, cognition and activities of daily living in aged care residents. Comprehensive measurement of frailty-related metrics may provide improved understanding of frailty progression at later life stages. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40520-023-02491-y. |
format | Online Article Text |
id | pubmed-10520153 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-105201532023-09-27 Correlation of frailty assessment metrics in one-year follow-up of aged care residents: a sub-study of a randomised controlled trial Andrade, A. Q. Widagdo, I. Lim, R. Kelly, T.-L. Parfitt, G. Pratt, N. Bilton, R. L. Roughead, E. E. Aging Clin Exp Res Original Article INTRODUCTION: Frailty is increasingly recognised as a dynamic syndrome, with multiple causes, dimensions and consequences. There is little understanding of how those frailty assessment metrics interact over time. The aim of this study was to describe the longitudinal correlation between five frailty metrics, namely multimorbidity, muscular strength, mood alterations, cognitive capacity, and functional capacity in a cohort study of aged care (nursing home) residents. METHODS: 248 aged care residents with Frailty Index at baseline of < 0.4 and no dementia were followed for 12 months. A multimorbidity score and an activity of daily living limitation score were created using individual items of the Frailty Index. Muscular strength was measured by grip strength. Cognitive capacity was measured using the Montreal Cognitive Assessment (MoCA) test. Mood alterations were measured using the anxiety/depression screening question from EQ-5D. We analysed the inter-individual correlation at baseline, association between baseline and future change, and within-individual correlation at baseline, 6 and 12 months. RESULTS: Population analysis shows that metrics were not associated at baseline. All of the studied metrics at baseline were associated with change in 12 months, with the exception of anxiety/depression scores. Pairwise within-individual correlation was strong between MoCA and grip strength (0.13, p = 0.02) and activity of daily living (− 0.48, p < 0.001), and between activities of daily living and multimorbidity index (0.28, p < 0.001). No within-individual correlation was found between anxiety depression score and other metrics. CONCLUSION: The results suggest an interdependence between comorbidities, physical capacity, cognition and activities of daily living in aged care residents. Comprehensive measurement of frailty-related metrics may provide improved understanding of frailty progression at later life stages. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40520-023-02491-y. Springer International Publishing 2023-07-14 2023 /pmc/articles/PMC10520153/ /pubmed/37452224 http://dx.doi.org/10.1007/s40520-023-02491-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Article Andrade, A. Q. Widagdo, I. Lim, R. Kelly, T.-L. Parfitt, G. Pratt, N. Bilton, R. L. Roughead, E. E. Correlation of frailty assessment metrics in one-year follow-up of aged care residents: a sub-study of a randomised controlled trial |
title | Correlation of frailty assessment metrics in one-year follow-up of aged care residents: a sub-study of a randomised controlled trial |
title_full | Correlation of frailty assessment metrics in one-year follow-up of aged care residents: a sub-study of a randomised controlled trial |
title_fullStr | Correlation of frailty assessment metrics in one-year follow-up of aged care residents: a sub-study of a randomised controlled trial |
title_full_unstemmed | Correlation of frailty assessment metrics in one-year follow-up of aged care residents: a sub-study of a randomised controlled trial |
title_short | Correlation of frailty assessment metrics in one-year follow-up of aged care residents: a sub-study of a randomised controlled trial |
title_sort | correlation of frailty assessment metrics in one-year follow-up of aged care residents: a sub-study of a randomised controlled trial |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520153/ https://www.ncbi.nlm.nih.gov/pubmed/37452224 http://dx.doi.org/10.1007/s40520-023-02491-y |
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