Topological regulation of a transmembrane protein by luminal-to-cytosolic retrotranslocation of glycosylated sequence

Transmembrane proteins must adopt proper topology to perform their functions. We previously demonstrated that ceramide regulates TM4SF20 (transmembrane 4 L6 family 20) by altering the topology of the transmembrane protein, but the underlying mechanism remains obscure. Here we report that TM4SF20 is...

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Detalles Bibliográficos
Autores principales: Wang, Jingcheng, Han, Sungwon, Ye, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520219/
https://www.ncbi.nlm.nih.gov/pubmed/36972171
http://dx.doi.org/10.1016/j.celrep.2023.112311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520219/
https://www.ncbi.nlm.nih.gov/pubmed/36972171
http://dx.doi.org/10.1016/j.celrep.2023.112311

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