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Bayesian multivariate genetic analysis improves translational insights

While lipid traits are known essential mediators of cardiovascular disease, few approaches have taken advantage of their shared genetic effects. We apply a Bayesian multivariate size estimator, mash, to GWAS of four lipid traits in the Million Veterans Program (MVP) and provide posterior mean and lo...

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Detalles Bibliográficos
Autores principales:	Urbut, Sarah M., Koyama, Satoshi, Hornsby, Whitney, Bhukar, Rohan, Kheterpal, Sumeet, Truong, Buu, Selvaraj, Margaret S., Neale, Benjamin, O’Donnell, Christopher J., Peloso, Gina M., Natarajan, Pradeep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520309/ https://www.ncbi.nlm.nih.gov/pubmed/37766997 http://dx.doi.org/10.1016/j.isci.2023.107854

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