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Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15

The noncoding genome presents a largely untapped source of new biological insights, including thousands of long noncoding RNA (lncRNA) loci. While lncRNA dysregulation has been reported in myeloid malignancies, their functional relevance remains to be systematically interrogated. We performed CRISPR...

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Detalles Bibliográficos
Autores principales: Ng, Michelle, Verboon, Lonneke, Issa, Hasan, Bhayadia, Raj, Vermunt, Marit Willemijn, Winkler, Robert, Schüler, Leah, Alejo, Oriol, Schuschel, Konstantin, Regenyi, Eniko, Borchert, Dorit, Heuser, Michael, Reinhardt, Dirk, Yaspo, Marie-Laure, Heckl, Dirk, Klusmann, Jan-Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520325/
https://www.ncbi.nlm.nih.gov/pubmed/37766974
http://dx.doi.org/10.1016/j.isci.2023.107844

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