Cargando…
Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15
The noncoding genome presents a largely untapped source of new biological insights, including thousands of long noncoding RNA (lncRNA) loci. While lncRNA dysregulation has been reported in myeloid malignancies, their functional relevance remains to be systematically interrogated. We performed CRISPR...
Autores principales: | Ng, Michelle, Verboon, Lonneke, Issa, Hasan, Bhayadia, Raj, Vermunt, Marit Willemijn, Winkler, Robert, Schüler, Leah, Alejo, Oriol, Schuschel, Konstantin, Regenyi, Eniko, Borchert, Dorit, Heuser, Michael, Reinhardt, Dirk, Yaspo, Marie-Laure, Heckl, Dirk, Klusmann, Jan-Henning |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520325/ https://www.ncbi.nlm.nih.gov/pubmed/37766974 http://dx.doi.org/10.1016/j.isci.2023.107844 |
Ejemplares similares
-
The megakaryocytic transcription factor ARID3A suppresses leukemia
pathogenesis
por: Alejo-Valle, Oriol, et al.
Publicado: (2022) -
RUNX1 isoform disequilibrium promotes the development of trisomy 21–associated myeloid leukemia
por: Gialesaki, Sofia, et al.
Publicado: (2023) -
PB1813: REGULATORY MECHANISMS AND THERAPEUTIC POTENTIAL OF THE DLK1-DIO3 LOCUS IN PEDIATRIC ACUTE MEGAKARYOBLASTIC LEUKEMIA
por: Verboon, Lonneke, et al.
Publicado: (2023) -
P419: HARNESSING MIRNA-193B-3P MIMIC AS A POTENT THERAPEUTIC OPTION IN ACUTE MYELOID LEUKEMIA
por: Issa, Hasan, et al.
Publicado: (2023) -
Preclinical testing of miRNA-193b-3p mimic in acute myeloid leukemias
por: Issa, Hasan, et al.
Publicado: (2023)