Impaired pre-synaptic plasticity and visual responses in auxilin-knockout mice

Auxilin (DNAJC6/PARK19), an endocytic co-chaperone, is essential for maintaining homeostasis in the readily releasable pool (RRP) by aiding clathrin-mediated uncoating of synaptic vesicles. Its loss-of-function mutations, observed in familial Parkinson’s disease (PD), lead to basal ganglia motor def...

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Detalles Bibliográficos
Autores principales: Cheng, Xi, Tang, Yu, Vidyadhara, D.J., Li, Ben-Zheng, Zimmerman, Michael, Pak, Alexandr, Nareddula, Sanghamitra, Edens, Paige Alyssa, Chandra, Sreeganga S., Chubykin, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520332/
https://www.ncbi.nlm.nih.gov/pubmed/37766983
http://dx.doi.org/10.1016/j.isci.2023.107842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520332/
https://www.ncbi.nlm.nih.gov/pubmed/37766983
http://dx.doi.org/10.1016/j.isci.2023.107842

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