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Hypoxia Primes Human ISCs for Interleukin-Dependent Rescue of Stem Cell Activity

BACKGROUND AND AIMS: Hypoxia in the intestinal epithelium can be caused by acute ischemic events or chronic inflammation in which immune cell infiltration produces inflammatory hypoxia starving the mucosa of oxygen. The epithelium has the capacity to regenerate after some ischemic and inflammatory c...

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Detalles Bibliográficos
Autores principales: Rivera, Kristina R., Bliton, R. Jarrett, Burclaff, Joseph, Czerwinski, Michael J., Liu, Jintong, Trueblood, Jessica M., Hinesley, Caroline M., Breau, Keith A., Deal, Halston E., Joshi, Shlok, Pozdin, Vladimir A., Yao, Ming, Ziegler, Amanda L., Blikslager, Anthony T., Daniele, Michael A., Magness, Scott T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520368/
https://www.ncbi.nlm.nih.gov/pubmed/37562653
http://dx.doi.org/10.1016/j.jcmgh.2023.07.012