A novel stop codon mutation in STK11 gene is associated with Peutz-Jeghers Syndrome and elevated cancer risk: a case study

Based on the analysis of patients with Peutz-Jeghers syndrome (PJS), Serine threonine kinase11 (STK11) is known as a tumor suppressor gene, which is involved in cell polarization, regulation of apoptosis, and DNA damage response. In this case report study, we examined STK11 gene sequencing in a 42-y...

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Detalles Bibliográficos
Autores principales: Khanabadi, Binazir, Najafgholizadeh Seyfi, Diba, Rejali, Leili, Taleghani, Mohammad Yaghoob, Tavallaei, Mehdi, Shahrokh, Shabnam, Daskar Abkenar, Elahe, Naderi Noukabadi, Fatemeh, Asadzadeh Aghdaei, Hamid, Nazemalhosseini Mojarad, Ehsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520397/
https://www.ncbi.nlm.nih.gov/pubmed/37767326
http://dx.doi.org/10.22037/ghfbb.v16i2.2751

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