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Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case report

KEY CLINICAL MESSAGE: Neurogenic fever (NF) is a potentially life‐threatening complication commonly seen in patients with pontine hemorrhage. This case report highlights the successful use of oral baclofen and propranolol as an effective treatment strategy to manage NF. ABSTRACT: Neurogenic fever (N...

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Autores principales: Poudel, Saroj, Chalise, Rupak, Bist, Manoj, Regmi, Ashim, Ghimire, Anup, Khanal, Kishor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520415/
https://www.ncbi.nlm.nih.gov/pubmed/37767152
http://dx.doi.org/10.1002/ccr3.7956
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author Poudel, Saroj
Chalise, Rupak
Bist, Manoj
Regmi, Ashim
Ghimire, Anup
Khanal, Kishor
author_facet Poudel, Saroj
Chalise, Rupak
Bist, Manoj
Regmi, Ashim
Ghimire, Anup
Khanal, Kishor
author_sort Poudel, Saroj
collection PubMed
description KEY CLINICAL MESSAGE: Neurogenic fever (NF) is a potentially life‐threatening complication commonly seen in patients with pontine hemorrhage. This case report highlights the successful use of oral baclofen and propranolol as an effective treatment strategy to manage NF. ABSTRACT: Neurogenic fever (NF) is a common complication following pontine hemorrhage and poses significant challenges for clinicians in terms of diagnosis, management, and patient outcomes. This study delves into the efficacy of treatment methods involving baclofen and propranolol for neurogenic fever in patients with pontine hemorrhage. The results demonstrated a significant reduction in the duration and intensity of fever. Moreover, the treatment modality was well‐tolerated and devoid of any adverse effects. These findings suggest that the use of oral baclofen and propranolol may be a promising therapeutic option for managing neurogenic fever in patients with pontine hemorrhage.
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spelling pubmed-105204152023-09-27 Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case report Poudel, Saroj Chalise, Rupak Bist, Manoj Regmi, Ashim Ghimire, Anup Khanal, Kishor Clin Case Rep Case Report KEY CLINICAL MESSAGE: Neurogenic fever (NF) is a potentially life‐threatening complication commonly seen in patients with pontine hemorrhage. This case report highlights the successful use of oral baclofen and propranolol as an effective treatment strategy to manage NF. ABSTRACT: Neurogenic fever (NF) is a common complication following pontine hemorrhage and poses significant challenges for clinicians in terms of diagnosis, management, and patient outcomes. This study delves into the efficacy of treatment methods involving baclofen and propranolol for neurogenic fever in patients with pontine hemorrhage. The results demonstrated a significant reduction in the duration and intensity of fever. Moreover, the treatment modality was well‐tolerated and devoid of any adverse effects. These findings suggest that the use of oral baclofen and propranolol may be a promising therapeutic option for managing neurogenic fever in patients with pontine hemorrhage. John Wiley and Sons Inc. 2023-09-25 /pmc/articles/PMC10520415/ /pubmed/37767152 http://dx.doi.org/10.1002/ccr3.7956 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Poudel, Saroj
Chalise, Rupak
Bist, Manoj
Regmi, Ashim
Ghimire, Anup
Khanal, Kishor
Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case report
title Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case report
title_full Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case report
title_fullStr Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case report
title_full_unstemmed Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case report
title_short Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case report
title_sort use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520415/
https://www.ncbi.nlm.nih.gov/pubmed/37767152
http://dx.doi.org/10.1002/ccr3.7956
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