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Prevalence of osteoporosis in patients awaiting unicompartmental knee arthroplasty: a cross-sectional study

OBJECTIVES: Osteoporosis may contribute to failure of unicompartmental knee arthroplasty (UKA), yet the prevalence of osteoporosis in the population awaiting UKA has not been adequately studied. The objectives of this study were to report the prevalence of osteoporosis in people awaiting UKA and the...

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Autores principales: Zhuang, Zhikun, Huang, Changyu, Chen, Xianyi, Wei, Qiushi, Guo, Jinhua, Xu, Zhiqing, Wu, Rongkai, Wu, Zhaoke, Xu, Fudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520455/
https://www.ncbi.nlm.nih.gov/pubmed/37766681
http://dx.doi.org/10.3389/fendo.2023.1224890
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author Zhuang, Zhikun
Huang, Changyu
Chen, Xianyi
Wei, Qiushi
Guo, Jinhua
Xu, Zhiqing
Wu, Rongkai
Wu, Zhaoke
Xu, Fudong
author_facet Zhuang, Zhikun
Huang, Changyu
Chen, Xianyi
Wei, Qiushi
Guo, Jinhua
Xu, Zhiqing
Wu, Rongkai
Wu, Zhaoke
Xu, Fudong
author_sort Zhuang, Zhikun
collection PubMed
description OBJECTIVES: Osteoporosis may contribute to failure of unicompartmental knee arthroplasty (UKA), yet the prevalence of osteoporosis in the population awaiting UKA has not been adequately studied. The objectives of this study were to report the prevalence of osteoporosis in people awaiting UKA and the rate of anti-osteoporosis treatment, and to explore factors associated with osteoporosis prevalence in people awaiting UKA. METHODS: Participants awaiting UKA from January 2019 to May 2023 were consecutively enrolled. Participants ‘ age, gender, BMI, knee K-L score, VAS score, history of previous DXA testing, history of anti-osteoporosis treatment, and possible underlying risk factors were recorded. All participants were given a dual-energy x-ray absorptiometry (DXA) test after the visit. The diagnosis of osteoporosis was made according to the World Health Organization criteria. Compare the prevalence of osteoporosis between people waiting for UKA and the general population. Risk factors associated with osteoporosis were analyzed using multiple linear regression and binary logistic regression models. RESULTS: A total of 340 participants were included in the study, 259 in female and 81 in male, with a mean age of 63.53 years (range: 41-84 years), and all participants completed UKA and had DXA prior to UKA. The prevalence of osteoporosis was 40.88% (44.79% in female and 28.40% in male). The prevalence of osteoporosis was higher in female than in male (p<0.001). The prevalence of osteoporosis in the population waiting for UKA was significantly higher than that in the general population (p < 0.001). DXA testing was performed in 12.06% within 1 year prior to the visit. The percentage of those who had received anti-osteoporosis treatment was 20.59% (20.86% in osteoporosis, 22.39% in Osteopenia and 16.42% in normal bone mass). The correlation between age, gender, body mass index, visual analogue scale score and osteoporosis was statistically significant. CONCLUSION: Osteoporosis is common in people waiting for UKA, but screening and treatment rates are low. Female patients of advanced age and low weight combined with significant pain should be considered for osteoporosis screening and appropriate treatment before UKA.
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spelling pubmed-105204552023-09-27 Prevalence of osteoporosis in patients awaiting unicompartmental knee arthroplasty: a cross-sectional study Zhuang, Zhikun Huang, Changyu Chen, Xianyi Wei, Qiushi Guo, Jinhua Xu, Zhiqing Wu, Rongkai Wu, Zhaoke Xu, Fudong Front Endocrinol (Lausanne) Endocrinology OBJECTIVES: Osteoporosis may contribute to failure of unicompartmental knee arthroplasty (UKA), yet the prevalence of osteoporosis in the population awaiting UKA has not been adequately studied. The objectives of this study were to report the prevalence of osteoporosis in people awaiting UKA and the rate of anti-osteoporosis treatment, and to explore factors associated with osteoporosis prevalence in people awaiting UKA. METHODS: Participants awaiting UKA from January 2019 to May 2023 were consecutively enrolled. Participants ‘ age, gender, BMI, knee K-L score, VAS score, history of previous DXA testing, history of anti-osteoporosis treatment, and possible underlying risk factors were recorded. All participants were given a dual-energy x-ray absorptiometry (DXA) test after the visit. The diagnosis of osteoporosis was made according to the World Health Organization criteria. Compare the prevalence of osteoporosis between people waiting for UKA and the general population. Risk factors associated with osteoporosis were analyzed using multiple linear regression and binary logistic regression models. RESULTS: A total of 340 participants were included in the study, 259 in female and 81 in male, with a mean age of 63.53 years (range: 41-84 years), and all participants completed UKA and had DXA prior to UKA. The prevalence of osteoporosis was 40.88% (44.79% in female and 28.40% in male). The prevalence of osteoporosis was higher in female than in male (p<0.001). The prevalence of osteoporosis in the population waiting for UKA was significantly higher than that in the general population (p < 0.001). DXA testing was performed in 12.06% within 1 year prior to the visit. The percentage of those who had received anti-osteoporosis treatment was 20.59% (20.86% in osteoporosis, 22.39% in Osteopenia and 16.42% in normal bone mass). The correlation between age, gender, body mass index, visual analogue scale score and osteoporosis was statistically significant. CONCLUSION: Osteoporosis is common in people waiting for UKA, but screening and treatment rates are low. Female patients of advanced age and low weight combined with significant pain should be considered for osteoporosis screening and appropriate treatment before UKA. Frontiers Media S.A. 2023-09-11 /pmc/articles/PMC10520455/ /pubmed/37766681 http://dx.doi.org/10.3389/fendo.2023.1224890 Text en Copyright © 2023 Zhuang, Huang, Chen, Wei, Guo, Xu, Wu, Wu and Xu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Zhuang, Zhikun
Huang, Changyu
Chen, Xianyi
Wei, Qiushi
Guo, Jinhua
Xu, Zhiqing
Wu, Rongkai
Wu, Zhaoke
Xu, Fudong
Prevalence of osteoporosis in patients awaiting unicompartmental knee arthroplasty: a cross-sectional study
title Prevalence of osteoporosis in patients awaiting unicompartmental knee arthroplasty: a cross-sectional study
title_full Prevalence of osteoporosis in patients awaiting unicompartmental knee arthroplasty: a cross-sectional study
title_fullStr Prevalence of osteoporosis in patients awaiting unicompartmental knee arthroplasty: a cross-sectional study
title_full_unstemmed Prevalence of osteoporosis in patients awaiting unicompartmental knee arthroplasty: a cross-sectional study
title_short Prevalence of osteoporosis in patients awaiting unicompartmental knee arthroplasty: a cross-sectional study
title_sort prevalence of osteoporosis in patients awaiting unicompartmental knee arthroplasty: a cross-sectional study
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520455/
https://www.ncbi.nlm.nih.gov/pubmed/37766681
http://dx.doi.org/10.3389/fendo.2023.1224890
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