Lymphadenitis caused by Purpureocillium lilacinum in a patient with CARD9 deficiency

We hereby make the first report of a case of mycosis caused by Purpureocillium lilacinum in CARD9 deficiency. A 40-year-old woman complained of lymph node swellings in the left cervical area. She also had chronic mucocutaneous candidiasis (CMC), and was found to have CARD9 deficiency. Lymphadenitis...

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Detalles Bibliográficos
Autores principales: Majima, Hidetaka, Inoue, Yuzaburo, Otsuka, Yuichiro, Yaguchi, Takashi, Watanabe, Akira, Kamei, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10520493/
https://www.ncbi.nlm.nih.gov/pubmed/37767185
http://dx.doi.org/10.1016/j.mmcr.2023.100609
Descripción
Sumario:We hereby make the first report of a case of mycosis caused by Purpureocillium lilacinum in CARD9 deficiency. A 40-year-old woman complained of lymph node swellings in the left cervical area. She also had chronic mucocutaneous candidiasis (CMC), and was found to have CARD9 deficiency. Lymphadenitis by P. lilacinum was confirmed. The diagnosis was difficult, as culturing the biopsy specimen at a cautiously selected temperature (25 °C) and genetic analysis were both required. Oral administration of voriconazole improved her lymphadenopathy.

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